Korean J Nephrol.  2010 Mar;29(2):250-255.

A Case of Tubulointerstitial Nephritis and Uveitis Syndrome in An Old Age Female

• Kim DH
• Jang YS
• Do WS
• Oh DM
• Kim SH
• Kwak EK
• Lee DH

Abstract

We report a case of tubulointerstitial nephritis and uveitis (TINU) syndrome in an old age female. A 66-year-old woman presented with nonspecific systemic symptoms and severe renal dysfunction. Renal biopsy showed acute interstitial nephritis and ophthalmologic examination revealed bilateral panuveitis. Evaluations for connective tissue diseases and infectious diseases were negative. She was treated with total eight sessions of hemodialysis, oral steroids and topical steroids. Renal function had improved significantly and remained stable at follow-up, although it did not fully recovered yet. TINU syndrome should be considered in cases of unexplained tubulointerstitial nephritis, especially in the presence of ocular symptom.

Keyword

Tubulointerstitial nephritis; Uveitis; Acute kidney failure

MeSH Terms

Acute Kidney Injury
Aged
Biopsy
Communicable Diseases
Connective Tissue Diseases
Female
Follow-Up Studies
Humans
Nephritis, Interstitial
Panuveitis
Renal Dialysis
Steroids
Uveitis
Nephritis, Interstitial
Steroids
Uveitis