Korean J Dermatol.  2008 Oct;46(10):1387-1390.

A Case of Squamous Cell Carcinoma with Nodal MetastasisConfirmed by Sentinel Lymph Node Biopsy

• Chi SG
• Kim HY
• Park BC
• Lee SJ
• Choe YS
• Kim BS
• Kim DW

Abstract

Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer and the majority of such patients can be easily treated with a relatively low risk of recurrence and metastasis. However, there are subgroups of SCC that are at a higher risk, depending on patient's or tumor's characteristics. A greater part of the metastases from these high-risked SCCs spread towards the regional lymph nodes, whereas distant metastases are relatively uncommon. Early identification of nodal metastasis can allow the selective and timely inclusion of possible high-risked SCC patients into more aggressive treatments and meticulous follow-up protocols for achieving potential survival benefit. Therefore, sentinel lymph node biopsy (SLNB) is popular in the management of malignant melanoma, and it may also be useful to detect regional metastasis of high-risked SCCs. This procedure could also spare node-negative patients the morbidity of unnecessary additional therapy, like elective lymph node dissection. We report herein on a case of SCC with regional nodal metastasis, which is confirmed by SLNB.

Keyword

Nodal metastasis; Sentinel lymph node biopsy; Squamous cell carcinoma

MeSH Terms

Carcinoma, Squamous Cell
Follow-Up Studies
Humans
Lymph Node Excision
Lymph Nodes
Melanoma
Neoplasm Metastasis
Nitriles
Pyrethrins
Recurrence
Sentinel Lymph Node Biopsy
Skin Neoplasms
Nitriles
Pyrethrins