Korean J Dermatol.  2009 Mar;47(3):326-329.

A Case of Extraocular Sebaceous Carcinoma Arising from Nevus Sebaceus

• Nam JH
• Choi YJ
• Kim TH
• Lee GY
• Kim WS
• Kim KJ

Abstract

Sebaceous carcinoma (SC) is a slow-growing, locally aggressive tumor with the high potency of metastatic spread. This neoplasm frequently arises from the sebaceous glands of the eyelid and exceptionally from extraocular sites. Approximately one-quarter of all reported cases of SC are extraocular. We observed a 42-year-old woman with an crusted erythematous to brownish plaque on her scalp. The biopsy specimen showed that multiple lobules were composed of foamy-cytoplasmic cells and sebocytes which show pleomorphism and atypia. For the immunohistochemistry, abundant tumor cells (with the expressions of epithelial membrane antigens and cytokeratin) were found within the masses. We present here a case of SC of the scalp arising from a previous lesion clinically compatible with a nevus sebaceous.

Keyword

Nevus sebaceus; Scalp; Sebaceous carcinoma

MeSH Terms

Adult
Biopsy
Eyelids
Female
Humans
Immunohistochemistry
Mucin-1
Nevus
Scalp
Sebaceous Glands
Mucin-1