J Gynecol Oncol.  2012 Jul;23(3):201-204. 10.3802/jgo.2012.23.3.201.

Successful term pregnancies after laparoscopic excision of poorly differentiated Sertoli-Leydig cell tumor of the ovary

• Gowri V
• Koliyadan
• Al Hamdani A
• Al Kindy N

• KMID: 2245181
• DOI: http://doi.org/10.3802/jgo.2012.23.3.201

Abstract

Ovarian Sertoli-Leydig cell tumors are rare sex cord-stromal tumors, accounting for less than 1% of ovarian tumors. Majority of these tumors are benign and unilateral, only 3-5% are bilateral. These patients present with clinical features of virilization due to excessive secretion of testosterone from the tumor, however 50% may have no endocrine symptoms. We report a case of poorly differentiated Sertoli-Leydig cell tumour in a woman diagnosed during routine investigation of infertility. She had two spontaneous successful pregnancies after tumor excision laparoscopically.

Keyword

Laparoscopy; Malignancy; Pregnancy; Sex-cord stromal tumor

MeSH Terms

Accounting
Female
Humans
Infertility
Laparoscopy
Ovary
Pregnancy
Sertoli-Leydig Cell Tumor
Sex Cord-Gonadal Stromal Tumors
Testosterone
Virilism
Sertoli-Leydig Cell Tumor
Testosterone

Figure

• 

  Fig. 1 Axial fat saturated T2 weighted image of pelvis showing uterus and both ovaries identified a heterogeneous solid mass close to the left ovary (arrow) and a small amount of free fluid in the pelvis (arrowheads).

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  Fig. 2 (A) Sertoli cells surrounded by Leydig cells (H&E, ×60). (B) Immunohistochemistry studies showing strong positive staining for inhibin (×20).

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