Korean J Gastrointest Endosc.  2005 Sep;31(3):147-154.

The Value of Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in the Differential Diagnosis of Pancreatic Mass

  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. dwseoamc@amc.seoul.kr
  • 2Department of Internal Medicine, Dongguk University International Hospital, Dongguk University College of Medicine, Goyang, Korea.


Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a technique used to distinguish benign and malignant pancreatic mass histologically. The aim of this study was to determine the value and safety of EUS-FNA for the differential diagnosis of pancreatic solid mass.
The records of forty patients (M : F=24 : 16, median age: 56 yr) who underwent EUS-FNA for the diagnosis of pancreatic solid masses between October 2003 and July 2004 were analyzed. Histological findings obtained by EUS-FNA were compared with the final diagnosis. The sensitivity, specificity, overall diagnostic accuracy, and the rate of complication of EUS-FNA were analyzed.
The sites of the lesions were as follows: pancreatic head, n=20 (50%); body, n=10 (25%); tail, n=7 (18%); multifocal, n=3 (8%). The sensitivity, specificity, accuracy and negative predictive values were 71%, 78%, 73%, and 64%, respectively. The diagnostic accuracy was 90% in body lesions, however 65% in head lesions. Transient abdominal pain occurred in one patient (3%) after the procedure; however, there was no case of severe complication.CONCLUSIONS: EUS-FNA is shown to be an effective and safe procedure for establishing a tissue diagnosis in patients with solid pancreatic masses.


Endoscopic ultrasound guided fine needle aspiration; Pancreatic solid mass
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