Korean J Gastrointest Endosc.  2005 Sep;31(3):147-154.

The Value of Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in the Differential Diagnosis of Pancreatic Mass

• Cha JM
• Seo DW
• Lee SS
• Park DH
• Choi JS
• Ju YM
• Lee SK
• Kim MH
• Min YI

Abstract

BACKGROUND/AIMS
Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a technique used to distinguish benign and malignant pancreatic mass histologically. The aim of this study was to determine the value and safety of EUS-FNA for the differential diagnosis of pancreatic solid mass.
METHODS
The records of forty patients (M : F=24 : 16, median age: 56 yr) who underwent EUS-FNA for the diagnosis of pancreatic solid masses between October 2003 and July 2004 were analyzed. Histological findings obtained by EUS-FNA were compared with the final diagnosis. The sensitivity, specificity, overall diagnostic accuracy, and the rate of complication of EUS-FNA were analyzed.
RESULTS
The sites of the lesions were as follows: pancreatic head, n=20 (50%); body, n=10 (25%); tail, n=7 (18%); multifocal, n=3 (8%). The sensitivity, specificity, accuracy and negative predictive values were 71%, 78%, 73%, and 64%, respectively. The diagnostic accuracy was 90% in body lesions, however 65% in head lesions. Transient abdominal pain occurred in one patient (3%) after the procedure; however, there was no case of severe complication.CONCLUSIONS: EUS-FNA is shown to be an effective and safe procedure for establishing a tissue diagnosis in patients with solid pancreatic masses.

Keyword

Endoscopic ultrasound guided fine needle aspiration; Pancreatic solid mass

MeSH Terms

Abdominal Pain
Biopsy*
Diagnosis
Diagnosis, Differential*
Endoscopic Ultrasound-Guided Fine Needle Aspiration*
Head
Humans
Sensitivity and Specificity