Korean J Hepatobiliary Pancreat Surg.  2016 May;20(2):49-52. 10.14701/kjhbps.2016.20.2.49.

Changes in the types of liver diseases requiring hepatic resection: a single-institution experience of 9016 cases over a 10-year period

Affiliations
  • 1Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. shwang@amc.seoul.kr

Abstract

BACKGROUNDS/AIMS
To understand the changing demands for hepatic resection (HR), we collected data regarding HR performed in a tertiary centre over a period of 10 years.
METHODS
We carried out extensive search of institutional databases to identify HR cases performed between January 2005 and December 2014. A study cohort of 9,016 patients were divided into 5 disease categories, namely hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), intrahepatic duct stone disease (IHDS), colorectal cancer liver metastasis (CRLM), and uncommon/rare diseases (URD).
RESULTS
There were 5,661 (62.8%) HCC cases, followed by 1441 (16.0%) CRLM, 942 (10.5%) ICC, 638 (7.1%) IHDS and 334 (3.7%) URD. The number of annual HR cases gradually increased from 443 in 2005 to 1,260 in 2015. Annual HCC cases also gradually increased, but the annual proportion of HCC cases fluctuated narrowly between 58.3% and 70.2%. Annual CRLM cases increased rapidly, and their proportion increased progressively from 4.7% to 20.5%. Annual ICC cases increased slowly, and their annual proportion fluctuated between 7.2% and 15.6%. Annual IHDS cases decreased slowly, and their annual proportion decreased progressively from 17.2% to 3.4%, while annual URD cases fluctuated, with annual proportions varying between 2.3% and 5.6%.
CONCLUSIONS
Annual cases of HR increased over the last 10 years in a tertiary center probably due to a center-specific centralization effect. The number of CRLM cases increased rapidly; those of HCC and ICC increased gradually, and those of IHDS declined gradually. We believe that these results reflect real changes in the types of liver disease requiring HR.

Keyword

Hepatocellular carcinoma; Intrahepatic cholangiocarcinoma; Liver metastasis; Intrahepatic duct stone; Benign liver disease; Hepatic resection; Prevalence; Incidence

MeSH Terms

Carcinoma, Hepatocellular
Cholangiocarcinoma
Cohort Studies
Colorectal Neoplasms
Humans
Incidence
Liver Diseases*
Liver*
Neoplasm Metastasis
Prevalence

Figure

  • Fig. 1 Cumulative incidences of annual cases in the five disease categories. HCC, hepatocellular carcinoma; ICC, intrahepatic cholangiocarcinoma; IHDS, intrahepatic duct stone disease; CRLM, colorectal cancer liver metastasis; URD, uncommon or rare diseases.

  • Fig. 2 Changes in the incidences of annual cases per disease category.

  • Fig. 3 Changes in the proportions of annual cases per disease category.

  • Fig. 4 Changes in the proportions of annual cases in the hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) categories.


Cited by  4 articles

Surgical indications for focal nodular hyperplasia of the liver: Single-center experience of 48 adult cases
Jin-Min Jung, Shin Hwang, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung
Ann Hepatobiliary Pancreat Surg. 2019;23(1):8-12.    doi: 10.14701/ahbps.2019.23.1.8.

Clinicopathological correlation and post-resection outcomes of hepatic angiomyolipoma
Geunhyeok Yang, Shin Hwang, Chul-Soo Ahn, Ki-Hun Kim, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Gil-Chun Park, Seung-Mo Hong
Ann Hepatobiliary Pancreat Surg. 2021;25(2):215-220.    doi: 10.14701/ahbps.2021.25.2.215.

Living donor liver transplantation with total pancreatectomy and portal vein homograft replacement in a pediatric patient with advanced pancreatoblastoma
Jung-Man Namgoong, Shin Hwang, Seak Hee Oh, Kyung Mo Kim, Gil-Chun Park, Chul-Soo Ahn, Hyunhee Kwon, Yu Jeong Cho, Yong Jae Kwon
Ann Hepatobiliary Pancreat Surg. 2020;24(1):78-84.    doi: 10.14701/ahbps.2020.24.1.78.

Post-resection prognosis of patients with hepatic epithelioid hemangioendothelioma
Byeong-Gon Na, Shin Hwang, Chul-Soo Ahn, Ki-Hun Kim, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Seung-Mo Hong, Sung-Gyu Lee
Ann Surg Treat Res. 2021;100(3):137-143.    doi: 10.4174/astr.2021.100.3.137.


Reference

1. Jung KW, Won YJ, Kong HJ, Oh CM, Lee DH, Lee JS. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2011. Cancer Res Treat. 2014; 46:109–123. PMID: 24851102.
Article
2. Jung KW, Won YJ, Kong HJ, Oh CM, Cho H, Lee DH, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2012. Cancer Res Treat. 2015; 47:127–141. PMID: 25761484.
Article
3. Jung KW, Won YJ, Oh CM, Kong HJ, Cho H, Lee DH, et al. Prediction of cancer incidence and mortality in Korea, 2015. Cancer Res Treat. 2015; 47:142–148. PMID: 25779360.
Article
4. Hwang S, Lee YJ, Kim KH, Ahn CS, Moon DB, Ha TY, et al. The impact of tumor size on long-term survival outcomes after resection of solitary hepatocellular carcinoma: single-institution experience with 2558 patients. J Gastrointest Surg. 2015; 19:1281–1290. PMID: 25956724.
Article
5. Hwang S, Lee YJ, Kim KH, Ahn CS, Moon DB, Ha TY, et al. Long-term outcome after resection of huge hepatocellular carcinoma ≥ 10 cm: single-institution experience with 471 patients. World J Surg. 2015; 39:2519–2528. PMID: 26126423.
6. Yoon YS, Kim CW, Lim SB, Yu CS, Kim SY, Kim TW, et al. Palliative surgery in patients with unresectable colorectal liver metastases: a propensity score matching analysis. J Surg Oncol. 2014; 109:239–244. PMID: 24165972.
Article
7. Seo SI, Lim SB, Yoon YS, Kim CW, Yu CS, Kim TW, et al. Comparison of recurrence patterns between ≤5 years and >5 years after curative operations in colorectal cancer patients. J Surg Oncol. 2013; 108:9–13. PMID: 23754582.
8. Kim KH, Yoon YS, Yu CS, Kim TW, Kim HJ, Kim PN, et al. Comparative analysis of radiofrequency ablation and surgical resection for colorectal liver metastases. J Korean Surg Soc. 2011; 81:25–34. PMID: 22066097.
Article
9. Njei B. Changing pattern of epidemiology in intrahepatic cholangiocarcinoma. Hepatology. 2014; 60:1107–1108. PMID: 24327308.
Article
10. Lubezky N, Facciuto M, Harimoto N, Schwartz ME, Florman SS. Surgical treatment of intrahepatic cholangiocarcinoma in the USA. J Hepatobiliary Pancreat Sci. 2015; 22:124–130. PMID: 25187408.
Article
11. Yamamoto M, Ariizumi S. Surgical outcomes of intrahepatic cholangiocarcinoma. Surg Today. 2011; 41:896–902. PMID: 21748603.
Article
12. Hwang S, Lee YJ, Song GW, Park KM, Kim KH, Ahn CS, et al. Prognostic impact of tumor growth type on 7th AJCC staging system for intrahepatic cholangiocarcinoma: a single-center experience of 659 cases. J Gastrointest Surg. 2015; 19:1291–1304. PMID: 25820487.
Article
13. Cheon YK, Cho YD, Moon JH, Lee JS, Shim CS. Evaluation of long-term results and recurrent factors after operative and nonoperative treatment for hepatolithiasis. Surgery. 2009; 146:843–853. PMID: 19744434.
Article
14. Hoffmann K, Unsinn M, Hinz U, Weiss KH, Waldburger N, Longerich T, et al. Outcome after a liver resection of benign lesions. HPB (Oxford). 2015; 17:994–1000. PMID: 26456947.
Article
15. Ciria R, Cherqui D, Geller DA, Briceno J, Wakabayashi G. Comparative short-term benefits of laparoscopic liver resection: 9000 cases and climbing. Ann Surg. 2016; 263:761–777. PMID: 26700223.
16. Hau HM, Atanasov G, Tautenhahn HM, Ascherl R, Wiltberger G, Schoenberg MB, et al. The value of liver resection for focal nodular hyperplasia: resection yes or no? Eur J Med Res. 2015; 20:86. PMID: 26494164.
Article
Full Text Links
  • KJHBPS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr