Korean J Anesthesiol.  1990 Oct;23(5):779-785. 10.4097/kjae.1990.23.5.779.

A Clinical Study of T-cain and Dibucaine in Spinal Anesthesia

Affiliations
  • 1Department of Anesthesiology, Chonbuk National University, College of Medicine, Chonju, Korea.

Abstract

T-can is one of the most widely available local anesthetics for spinal anesthesia in Korea and we use T-cain almost exclusively. However, some anesthetists prefer other local anesthetics such as dibucaine, bupivacaine, or lidocaine for spinal anesthesia. We examined the hemodynamic effects, onset, spread, and duration of sensory and motor blockade following spinal anesthesia with 0.5% T-cain, 0.24% dibucaine, and 0.3% dibucaine. The results were as follows: 1) The blood pressure and pulse rate were decreased by all three drugs without significant difference among the three drugs. 2) The onset of sensory blockade was faster with T-cain than with dibucaine. T-cain containing 0.24% dibucaine had faster onset than the 0.3% solution. The spread of analgesia was also more rapid with T-cain than with dibucaine. 3) The motor blockade was significantly faster and more profound with T-cain than with dibucaine. 4) The duration of anesthesia was the shortest with T-cain containing 0.24% dibucaine and the longest with 0.3% dibucaine, but there was no statistical significance. From the above results, T-cain proved to be a more profound and shorter lasting local anesthetic than dibucaine. However, sensory and motor blockade produced by dibucaine were clinically acceptable. Therefore, both T-cain and dibucaine can be clinically available for spinal anesthesia.

Keyword

Spinal Anesthesia; T-cain; Dibucaine

MeSH Terms

Analgesia
Anesthesia
Anesthesia, Spinal*
Anesthetics, Local
Blood Pressure
Bupivacaine
Dibucaine*
Heart Rate
Hemodynamics
Korea
Lidocaine
Anesthetics, Local
Bupivacaine
Dibucaine
Lidocaine
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