Korean J Dermatol.  1983 Apr;21(2):189-193.

Adenosine Deaminase Activities in Sera and Erythrocytes of Leprosy Patients

• Choi YS
• Chun IK
• Kim YP

Abstract

Leprosy has two polar types. The one tuberculoid leprosy (TL) is characterized by well preserved cellular immunity with a good prognosia and the other lepromatous leprosy(LL) shows no cellular immunity with a poor prognosis. The preaent study was designed to measure the activity of adenosine deaminase (ADA) in sera and erythrocytes of leprosy patients, as it's activities are known to be decreased in immune deficiency diseases. There were no significant differences in the erythrocyte ADA activities among normal subjects(9. 60+4. 43 units/1012 cells), TL patients (7. 12+2. 51 units/1012 cells) and LL patients(6. 96+0. 81 units/1012 cells), The ADA activities in sera of TL patients(20.15+2. 90 units/L) did not differ from those of normal subjects(20.44+ 2. 07 units/L), but the LL patients(17. 52+3. 30 units/L) showed a slightly lowered activity than those of normal subjects.

MeSH Terms

Adenosine Deaminase*
Adenosine*
Deficiency Diseases
Erythrocytes*
Humans
Immunity, Cellular
Leprosy*
Leprosy, Tuberculoid
Prognosis
Adenosine
Adenosine Deaminase