Korean J Androl.  2008 Jun;26(2):91-95.

Correlation between Serum Testosterone and Lower Urinary Tract Symptoms in Men with Hypogonadism Symptoms

Affiliations
  • 1Department of Urology, The Catholic University of Korea College of Medicine, Seoul, Korea. ksw1227@catholic.ac.kr

Abstract

PURPOSE: We performed this study to estimate the correlation of serum testosterone and lower urinary tract symptom (LUTS) in adult hypogonadism patients.
MATERIALS AND METHODS
Medical records of ninety men over forty years old who have LUTS, International Prostate Symptom Score (IPSS) above 7 were reviewed. The correlations of serum testosterone level withage, International Prostate Symptom Score (IPSS), prostate volume, prostate specific antigen (PSA) and maximal flow rate were assessed using Spearman test. The statistical differences of IPSS, prostate volume, PSA and maximal flow rate in 3 groups of patients divided by serum testosterone levels(<2.0, 2.0-3.5, >3.5 ng/ml).
RESULTS
Serum testosterone level decreased according to increase of age (r=-0.28, p=0.07). Serum testosterone has no significant correlation with IPSS, prostate volume, PSA and maximal flow rate. There was no significant difference of IPSS, prostate volume, PSA and maximal flow rate according to the levels of testosterone.
CONCLUSIONS
Emerging from this analysis, clinical indexes of LUTS may not be connected with testosteronelevel and LUTS may not be affected by hypogonadism. Further more objective and sophisticated studies with large number of subjects are requested for the understanding of pathophysiology of LUTS in hypogonadism.

Keyword

Lower urinary tract symptom; Testosterone; Hypogonadism
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