Korean J Clin Pathol.
2001 Aug;21(4):260-263.
A Case of CD7+, CD4-, CD8-, CD3-acute T cell lymphoblastic leukemia
- Affiliations
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- 1Department of Clinical Pathology, Ewha Womans University, College of Medicine, Seoul, Korea.
- 2Department of Anatomic Pathology, Ewha Womans University, College of Medicine, Seoul, Korea.
Abstract
- A CD7 positive acute leukemia, lacking CD4, CD8, CD3, CD13 and CD33 expression may include 4 categories; acute T-cell leukemia, mixed lineage leukemia, acute undifferentiated leukemia and CD7 positive acute myeloid leukemia. Therefore, the expression of cyCD3 or the presence of TCR gene rearrangement can make the diagnosis of acute T-cell leukemia. We report a patient with acute T-cell lymphoblastic leukemia, showing CD7+, CD4-CD8-, and CD3-expression and TCR gamma gene rearrangement.
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