Korean Circ J.  2011 Jul;41(7):394-398. 10.4070/kcj.2011.41.7.394.

Associated Symptoms of Kawasaki Disease

• Yun SH
• Yang NR
• Park SA

• KMID: 2225103
• DOI: http://doi.org/10.4070/kcj.2011.41.7.394

Abstract

BACKGROUND AND OBJECTIVES
In addition to diagnostic criteria, a broad range of nonspecific clinical features can be found in patients with Kawasaki disease. This lack of specificity may cause confusion with other febrile illnesses and delay the diagnosis of Kawasaki disease. The purpose of this study is to describe common associated symptoms and their clinical significances in children affected with Kawasaki disease.
SUBJECTS AND METHODS
As a retrospective study, we reviewed the medical records of 121 children who were treated for Kawasaki disease at Presbyterian medical center from January 2005 to June 2010. All clinical symptoms, laboratory data and echocardiographic findings in patients with KD were collected and analyzed.
RESULTS
We found that there are 9 associated symptoms, namely cough, rhinorrhea, sputum, abdominal pain, vomiting, diarrhea, arthralgia, headache and seizure, which occur in patients with Kawasaki disease. Among the study group, there were only 32 children with no associated symptoms (26.4%). Patients with abdominal pain and headache had an older mean age than those without such symptoms. The incidence of seizure was significantly higher in incomplete Kawasaki disease patients compared with those with complete Kawasaki disease. Vomiting was highly associated with IVIG non-responder group.
CONCLUSION
To decrease the incidence of serious coronary complications due to delayed diagnosis, physicians need to be aware of the manifestations of Kawasaki disease and the possibility of associated symptoms, which, being unspecific, may otherwise not raise any red flags.

Keyword

Mucocutaneous lymph node syndrome; Signs and symptoms

MeSH Terms

Abdominal Pain
Arthralgia
Child
Cough
Delayed Diagnosis
Diarrhea
Headache
Humans
Immunoglobulins, Intravenous
Incidence
Medical Records
Mucocutaneous Lymph Node Syndrome
Protestantism
Retrospective Studies
Seizures
Sensitivity and Specificity
Sputum
Vomiting
Immunoglobulins, Intravenous

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