Kidney Res Clin Pract.  2014 Jun;33(2):106-108.

A case of reninoma with variant angina

Affiliations
  • 1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. ohchris@hanmail.net
  • 2Department of Urology, Seoul National University Hospital, Seoul, Korea.
  • 3Department of Pathology and Kidney Research Institute, Seoul National University Hospital, Seoul, Korea.
  • 4Department of Internal Medicine, Konkuk University Hospital, Seoul, Korea.

Abstract

Reninoma is a tumor of the renal juxtaglomerular cell apparatus that causes hypertension and hypokalemia because of hypersecretion of renin. We present a case of a 29-year-old female patient with reninoma and concomitant variant angina. The patient had uncontrolled hypertension and elevated plasma renin activity and aldosterone levels. Imaging studies revealed a mass in the left kidney, which was further confirmed as a renin-producing lesion via selective venous catheterization. During the evaluation, the patient had acute-onset chest pain that was diagnosed as variant angina after a provocation test. After partial nephrectomy, the plasma renin activity and plasma aldosterone levels decreased and blood pressure normalized. We report a case of reninoma with variant angina.

Keyword

Kidney neoplasms; Renin; Unstable angina

MeSH Terms

Adult
Aldosterone
Angina, Unstable
Blood Pressure
Catheterization
Catheters
Chest Pain
Female
Humans
Hypertension
Hypokalemia
Kidney
Kidney Neoplasms
Nephrectomy
Plasma
Renin
Aldosterone
Renin
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