Clin Endosc.  2015 Jan;48(1):81-84. 10.5946/ce.2015.48.1.81.

Colonic Lymphangiomatosis Resolved after Excisional Biopsy

Affiliations
  • 1Department of Internal Medicine, Sahmyook Medical Center, Seoul, Korea.
  • 2Department of Pathology, Sahmyook Medical Center, Seoul, Korea.
  • 3Division of Gastroenterology, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. chansshim@naver.com

Abstract

Lymphangioma is an uncommon malformation of the lymphatic system that involves a benign proliferation of the lymphatics, with no established treatment method. Multiple colonic lymphangioma, or colonic lymphangiomatosis, is an extremely rare condition. We report a case of colonic lymphangiomatosis that was detected during a colonoscopic examination conducted as part of a general health check-up. The lesion completely resolved after excisional biopsy.

Keyword

Colon; Excision; Lymphangioma; Lymphangiomatosis; Resolution

MeSH Terms

Biopsy*
Colon*
Lymphangioma
Lymphatic System

Figure

  • Fig. 1 Colonoscopy revealing a cluster of multiple cystic masses of various sizes and shapes with the same color and surface as the surrounding normal mucosa.

  • Fig. 2 Abdominal computed tomography scan showing normal colonic findings.

  • Fig. 3 (A) Lifting solution is injected around the cystic masses. (B) A snare is applied to the injected cystic mass. (C) Shrunken mass after incision.

  • Fig. 4 (A) Hematoxylin and eosin staining of normal colonic mucosa and a markedly dilated lymphatic vessel (×100). (B) CD34 expression in a lymphatic vessel. Smooth muscle cells and endothelial cells are located beneath the colonic mucosal glands (×100). (C) D2-40 expression (brown color) in a lymphatic vessel (×200).

  • Fig. 5 Normal colonic mucosa is seen on third colonoscopy. No abnormality including previous lymphangiomatosis is found.


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