Korean J Med.  2016 Jun;90(6):550-553. 10.3904/kjm.2016.90.6.550.

Acute Kidney Injury due to Rbadomyolysis Complicated with Zolpidem Overdose

Affiliations
  • 1Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. gwkang4540@hanmail.net

Abstract

Zolpidem (Stilnox®, Handok, Seoul, Korea) is a hypnotic imidazopyridine that is often used to treat insomnia because it has less abuse and addiction potential than benzodiazepines. Its side effects include headache, dizziness, and nausea, but these are mild. Zolpidem intoxication rarely has severe complications. Here, we report a case of acute kidney injury due to rhabdomyolysis related to zolpidem. A 51-year-old man was admitted with drowsy mentality after taking an overdose of zolpidem in a suicide attempt. Laboratory findings showed a blood urea nitrogen of 59.9 mg/dL, serum creatinine of 5.8 mg/dL, and creatine phosphokinase of 16,210 IU/L. Acute kidney injury associated with rhabdomyolysis complicating zolpidem intoxication was diagnosed. The patient was managed with hemodialysis and recovered completely in terms of renal function and muscle enzyme levels.

Keyword

Zolpidem; Acute kidney injury; Rhabdomyolysis

MeSH Terms

Acute Kidney Injury*
Benzodiazepines
Blood Urea Nitrogen
Creatine Kinase
Creatinine
Dizziness
Headache
Humans
Middle Aged
Nausea
Renal Dialysis
Rhabdomyolysis
Seoul
Sleep Initiation and Maintenance Disorders
Suicide
Benzodiazepines
Creatine Kinase
Creatinine
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