J Korean Ophthalmol Soc.  2016 Feb;57(2):195-199. 10.3341/jkos.2016.57.2.195.

The Effects of Surgical Punctual Occlusion on Patients with Aqueous Deficient Dry Eye

Affiliations
  • 1Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. crisim@korea.ac.kr

Abstract

PURPOSE
To analyze the improvement of symptoms and signs of dry eye after surgical punctual occlusion and to evaluate the effects of secondary systemic disease in dry eye patients.
METHODS
From March 2011 to July 2014, 15 eyes of 8 dry eye patients with a history of punctal plug insertion underwent surgical punctal occlusion. Schirmer test was measured based on mean 2.9 mm. The patients consisted of 4 dry eye patients with Sjogren's disease, 1 with rheumatoid arthritis, 1 with graft-versus-host disease (GVHD), and 2 with no secondary systemic disease. Preoperative and postoperative ophthalmic examinations of log MAR visual acuity, subjective symptoms, corneal staining (National Eye Institute [NEI] score), and tear break-up time (BUT) were performed and the effects of secondary systemic disease in dry eye patients were evaluated. The results of surgical punctual occlusion were analyzed.
RESULTS
All patients showed a statistically significant improvement of log MAR visual acuity, subjective symptoms, corneal staining (NEI score), and tear BUT. The patients with rheumatoid-related diseases showed improved symptoms after surgery, but the patient with GVHD showed no significant improvement after surgery. Among the study patients, 80.0% showed completely closed punctum and 20.0% showed partial recanalization.
CONCLUSIONS
Surgical punctal occlusion is an effective alternative in patients with severe aqueous deficient dry eye who show recurrent punctal plug loss or complications associated with punctal plugs.

Keyword

Corneal staining; Dry eye; Punctal occlusion; Sjogren syndrome

MeSH Terms

Arthritis, Rheumatoid
Graft vs Host Disease
Humans
Sjogren's Syndrome
Tears
Visual Acuity

Figure

  • Figure 1. Anterior segment photography of dry eye patient with rhematologic disease. (A) Pre-treatment (A-1: right/A-2: left). (B) After punctal plug insertion (B-1: right/B-2: left). (C) One month after surgical punctal occlusion (C-1: right/C-2: left).


Reference

1). Henrich CF, Ramulu PY, Akpek EK. Association of dry eye and inflammatory systemic diseases in a tertiary care–based sample. Cornea. 2014; 33:819–25.
Article
2). Willis RM, Folberg R, Krachmer JH, Holland EJ. The treatment of aqueous-deficient dry eye with removable punctal plugs. A clinical and impression-cytologic study. Ophthalmology. 1987; 94:514–8.
3). Gilbard JP, Rossi SR, Azar DT, Heyda KG. Effect of punctal occlusion by Freeman silicone plug insertion on tear osmolarity in dry eye disorders. CLAO J. 1989; 15:216–8.
4). Balaram M, Schaumberg DA, Dana MR. Efficacy and tolerability outcomes after punctal occlusion with silicone plugs in dry eye syndrome. Am J Ophthalmol. 2001; 131:30–6.
Article
5). Baxter SA, Laibson PR. Punctal plugs in the management of dry eyes. Ocul Surf. 2004; 2:255–65.
Article
6). Bourkiza R, Lee V. A review of the complications of lacrimal occlusion with punctal and canalicular plugs. Orbit. 2012; 31:86–93.
Article
7). Ohba E, Dogru M, Hosaka E, et al. Surgical punctal occlusion with a high heat-energy releasing cautery device for severe dry eye with recurrent punctal plug extrusion. Am J Ophthalmol. 2011; 151:483–7. e1.
Article
8). Yang HY, Fujishima H, Toda I, et al. Lacrimal punctal occlusion for the treatment of superior limbic keratoconjunctivitis. Am J Ophthalmol. 1997; 124:80–7.
Article
9). Law RW, Li RT, Lam DS, Lai JS. Efficacy of pressure topical anaesthesia in punctal occlusion by diathermy. Br J Ophthalmol. 2005; 89:1449–52.
Article
10). Benson DR, Hemmady PB, Snyder RW. Efficacy of laser punctal occlusion. Ophthalmology. 1992; 99:618–21.
Article
11). Liu D, Sadhan Y. Surgical punctal occlusion: a prospective study. Br J Ophthalmol. 2002; 86:1031–4.
Article
12). Vrabec MP, Elsing SH, Aitken PA. A prospective, randomized comparison of thermal cautery and argon laser for permanent punctal occlusion. Am J Ophthalmol. 1993; 116:469–71.
Article
13). Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J. 1995; 21:221–32.
14). Horwath-Winter J, Thaci A, Gruber A, Boldin I. Long-term retention rates and complications of silicone punctal plugs in dry eye. Am J Ophthalmol. 2007; 144:441–4.
Article
15). Kim BM, Osmanovic SS, Edward DP. Pyogenic granulomas after silicone punctal plugs: a clinical and histopathologic study. Am J Ophthalmol. 2005; 139:678–84.
Article
16). Kaido M, Goto E, Dogru M, Tsubota K. Punctal occlusion in the management of chronic Stevens-Johnson syndrome. Ophthalmology. 2004; 111:895–900.
Article
17). Holzchuh R, Osaki TH, et al. Two-year outcome of partial lacrimal punctal occlusion in the management of dry eye related to Sjögren syndrome. Curr Eye Res. 2011; 36:507–12.
Article
18). Lee JS, Choi W, Lee SS, Yoon KC. Prevalence and clinical aspects of Sjögren syndrome in dry eye patients. J Korean Ophthalmol Soc. 2012; 53:499–504.
Article
19). Schiffman RM, Christianson MD, Jacobsen G, et al. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000; 118:615–21.
Article
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