J Korean Ophthalmol Soc.  2010 Feb;51(2):159-163. 10.3341/jkos.2010.51.2.159.

Results of the Mixed Solution of Hyaluronate and Sodium Carboxymethylcellulose in Endonasal Dacryocystorhinostomy

Affiliations
  • 1Department of Ophthalmology, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. yswoph@catholic.ac.kr

Abstract

PURPOSE
To evaluate the long-term results of the application of a mixed solution of hyaluronate and sodium carboxymethlycellulose (HACMC, Guardix-sol) intraoperatively in endonasal dacryocystorhinostomy (Endo-DCR).
METHODS
In this retrospective randomized controlled study, Endo-DCR and silicone tube intubation were performed on 83 eyes of 83 patients who were diagnosed with nasolacrimal duct obstruction. In group A (40 patients, 40 eyes), HACMC was applied to the osteotomy site in the nasal cavity after standard Endo DCR procedure. In group B (43 patients, 43 eyes), a standard Endo-DCR procedure was performed without HACMC. The results for the two groups were evaluated by asking patients about the tearing condition and examining the patency of irrigation, complications, and related treatment.
RESULTS
There were no statistically significant differences in age, sex, silicone tube insertion duration, or mean follow-up time between the two groups. The primary success rates of the group A and the group B were 87.5% (35/40) and 81.4% (35/43), respectively. The final success rates after the revisonal surgery were 92.5% (37/40) and 86.0% (37/43), respectively, and there were no statistically significant differences between the two groups (P=0.348, Fisher's exact test).
CONCLUSIONS
Applying HACMC to the nasal cavity will be useful in treating patients with poor prognosis, although the higher average primary success rate of patients receiving HACMC, as compared to those who did not, was not statistically significant.

Keyword

Endonasal dacryocystorhinostomy; Hyaluronate and sodium carboxymethylcellulose (HACMC); Synechia

MeSH Terms

Carboxymethylcellulose Sodium
Dacryocystorhinostomy
Eye
Follow-Up Studies
Humans
Intubation
Nasal Cavity
Nasolacrimal Duct
Osteotomy
Prognosis
Retrospective Studies
Silicones
Sodium
Carboxymethylcellulose Sodium
Silicones
Sodium

Figure

  • Figure 1. 0.25% sodium hyaluronate + 0.49% carboxymethylcellulose (Gardix-sol, Hanmi MediCare, Korea).


Cited by  1 articles

Clinical Results of Anti-adhesion Adjuvants after Endonasal Dacryocystorhinostomy
Hye-Young Shin, Ji-Sun Paik, Suk-Woo Yang
Korean J Ophthalmol. 2018;32(6):433-437.    doi: 10.3341/kjo.2017.0124.


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