J Korean Surg Soc.  2009 Feb;76(2):94-99. 10.4174/jkss.2009.76.2.94.

Prognostic Factors and Clinicopathologic Features after Resection of Small Hepatocellular Carcinoma (< or =2 cm)

Affiliations
  • 1Department of Surgery, College of Medicine, Yeungnam University, Daegu, Korea. dslee@med.yu.ac

Abstract

PURPOSE
Hepatectomy has been regarded as the first treatment of choice for small hepatocellular carcinoma. However, hepatectomy for treatment of small hepatocellular carcinoma remains a critical issue. This study evaluates the role of treatment regarding the survival rate and clinicopathological features after resection of small hepatocellular carcinoma ((< or =2 cm)
METHODS
This retrospective study was based on the medical records of 48 small hepatocellular carcinoma (< or =2 cm) patients who received surgical hepatectomy from 1990 to 2005. Patients who revealed on postoperative pathologic reports were enrolled. The survival rate was analyzed according to clinicopathologic and therapeutic factors and we analyzed the pathologic features of the recurrence group.
RESULTS
The presence of liver cirrhosis, ICGR15 (Indocyanine green retension-15) was statistically significant in the univariate analysis. The vascular invasion rate and capsule formation rate was 90, 80% in the recurrence group.
CONCLUSION
In the small hepatocellular carcinoma ((< or =2 cm), the presence of liver cirrhosis, ICGR15 (Indocyanine green retension-15) should be checked to predict prognosis. The small hepatocellular carcinoma ((< or =2 cm) is similar to advanced hepatocellular carcinoma so hepatectomy may play an important role in the small hepatocellular carcinoma ((< or =2 cm).

Keyword

Small hepatocellular carcinoma ((< or =2 cm); Prognostic factors; Clinicopathologic factors

MeSH Terms

Carcinoma, Hepatocellular
Hepatectomy
Humans
Liver Cirrhosis
Medical Records
Prognosis
Recurrence
Retrospective Studies
Survival Rate
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