J Korean Soc Radiol.  2010 Jul;63(1):33-39. 10.3348/jksr.2010.63.1.33.

The Location and Size of Pulmonary Embolism in Antineoplastic Chemotherapy Patients

Affiliations
  • 1Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Korea. wckwon@yonsei.ac.kr
  • 2Department of Internal Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Korea.
  • 3Department of Prevent Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Korea.

Abstract

PURPOSE
To retrospectively evaluate the prevalent location and size of pulmonary embolism (PE) in anti-neoplastic chemotherapy patients by multidetector row CT (MDCT).
MATERIALS AND METHODS
This study was conducted on 101 patients that were positively diagnosed with PE by CT. Among these patients, 23 had received or were undergoing chemotherapy. The location and the mean size of the largest PE were compared between anti-neoplastic chemotherapy patients and non-cancer patients using the Chisquare test and paired t-test, respectively. We also used a multiple linear regression to assess the risk posed by the other risk factors of PE.
RESULTS
The most prevalent location of PE in patients on anti-neoplastic chemotherapy was in the lobar or segmental pulmonary arteries and was not significantly different from non-cancer patients. The size of the PE was smaller in patients on anti-neoplastic chemotherapy (1.14 mL [standard error = 0.29]) compared to non-cancer patients. (2.14 mL [standard error = 0.40]) (p < 0.05).
CONCLUSION
The size of PE is smaller in anti-neoplastic chemotherapy patients than in non-cancer patients.


MeSH Terms

Antineoplastic Combined Chemotherapy Protocols
Humans
Linear Models
Pulmonary Artery
Pulmonary Embolism
Retrospective Studies
Risk Factors
Tomography, X-Ray Computed
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