J Korean Pediatr Soc.  2000 Jun;43(6):846-850.

A Case of Chronic Granulomatous Disease in which Enterococci were Observed in Culture

• Cho KL
• Kim JH
• Kim EJ
• Yoo CW
• Kim CS
• Nho US
• Kim CK

Abstract

Chronic granulomatous disease(CGD) is a genetically inherited disorder caused by the failure of phagocytic cells to produce superoxide. It is characterized by frequent and uncontrollable infection which often lead to death in early childhood. The first clinical signs may be confined to skin and manifest themselves as abscesses, pyoderma, eczema or draining sinuses. The disease was first reported in 1957 and thereafter the biomolecular mechanism has been found. The first report in Korea was an autopsy case in 1979 and since then there have been a few case reports. This disease is diagnosed by symptoms, such as high fever, cervical lymphadenopathy, skin nodule, lung field infiltration, periumbilical abscess, liver abscess, pyoderma and pericordal abscess. The pathogen here were catalase producing bacteria and fungi. However, we have experienced a case of CGD, in which symptoms were perianal, scrotal abscesses and lung field nodular infiltration. In this case the pathogen was found as a catalase negative Enterococcus. (J Korean Pediatr Soc 2000;43-846-850)

Keyword

Chronic granulomatous disease; Catalase negative Enterococcus

MeSH Terms

Abscess
Autopsy
Bacteria
Catalase
Eczema
Enterococcus
Fever
Fungi
Granulomatous Disease, Chronic*
Korea
Liver Abscess
Lung
Lymphatic Diseases
Phagocytes
Pyoderma
Skin
Superoxides
Catalase
Superoxides