J Korean Ophthalmol Soc.
1995 Dec;36(12):2138-2141.
Tissue Plasminogen Activator for Treatment of Subretinal Hemorrhage
- Affiliations
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- 1Department of Ophthalmology, Catholic University, Medical College, Seoul, Korea.
Abstract
- We report removing a large subretinal hemorrhage by means of vitrectomy combined with the use of tissue plasminogen activator(tPA) to facilitate clot removal. A 25-year-old man had a 4 days history of visual loss in the right eye after blunt trauma. The right fundus had a large subretinal hemorrhage involving macula. Surgery was performed the following day. A small retinotomy was made, through which tPA was injected into the subretinal space and through which the dissolved clot was removed. The use of tPA minimizes surgical manipulation of the retina and greatly reduces the size of the retinotomy reguired for evacuation of subretinal bood. Although the long-term prognosis is guarded, this case does suggest that tPA may be a useful adjunct in managing of subretinal hemorrhage.
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