J Korean Soc Vasc Surg.  2005 Nov;21(2):105-112.

Buerger's Disease in Korea

Affiliations
  • 1Division of Vascular Surgery, Department of Surgery, Kang-Nam St. Mary's Hospital, College of Medicine, The Catholic University of Korea. johnpark@catholic.ac.kr
  • 2Division of Vascular Surgery, Department of Surgery, Asan Medical Center, College of Medicine, Ulsan University.
  • 3Gachon Medical School Gil Medical Center.
  • 4The Catholic University of Korea, Kangnam St. Mary's Hospital.
  • 5Kyungpook National University Hospital.
  • 6Kyunghee University Medical Center.
  • 7Keimyung University Dongsan Medical Center.
  • 8Kim's Clinic of Vascular Surgery.
  • 9Dankook University Hospital.
  • 10Daegu Catholic University Hospital.
  • 11Daegu Patima Hospital.
  • 12Boramae Hospital.
  • 13Seoul National University Hospital.
  • 14Sungkyunkwan University, Samsung Medical Center.
  • 15Sungkyunkwan University, Kangbuk Samsung Medical Center.
  • 16Soonchunhyang University Cheonan Hospital.
  • 17Yeungnam University Medical Center.
  • 18Ulsan University, Asan Medical Center1, Seoul.
  • 19Ulsan University Hospital.
  • 20Wonkwang University Hospital.
  • 21Inje University Paik Hospital.
  • 22Chonnam National University Hospital.
  • 23Hanyang University Medical Center.
  • 24Hanil Hospital.

Abstract

PURPOSE
Buerger's disease (Thromboangiitis obliterans, TAO) is characterized by non- atheromatous inflammatory disease, and segmental inflammatory thrombotic occlusions of the small & middle-sized arteries and veins of the upper or lower extremities. Any epidemiological study of Buerger's disease in Korea has not been carried out until now. This study was undertaken to investigate the incidence of Buerger's disease in Korea among the patients suffering with arterial disease.
METHODS
We collected and analyzed the data on 11,128 patients who were admitted to or visited the participating 22 hospitals for chronic arterial diseases throughout the major region of the South Korea from January 1986 to December 2003. The clinical diagnostic inclusion criteria for Buerger's disease were the followings: (1) a history of smoking or tobacco abuse; (2) an age of onset less than 50 years; (3) infrapopliteal, segmental arterial occlusions with sparing of the proximal vasculature; (4) frequent distal upper extremity arterial involvement (Raynaud's syndrome or digital ulceration) or-superficial phlebitis; and (5) the absence of arteriosclerotic risk factors other than smoking.
RESULTS
The incidence rate of Buerger's disease among the arterial disease (11,128 patients) was 93 patients (0.83%) when the strict criteria of Shionoya was applied. 699 male-patients (6.55%) and 30 female patients (4.12%) who met the less strict criteria (the extended clinical diagnostic criteria group) were also reviewed. The 4th and 5th decades were the most common ages with-249 patients (34.2%) and 222 patients (30.5%) respectively, being found at these ages. The mean age was 40.4+/-1.6 years (age range: 16~83 years) and this was similar in both the strict criteria group and the less strict criteria group.
CONCLUSIONS
This study suggests there was a low incidence of Buerger's disease in Korea among the patients who visited the participating hospitals when the strict diagnostic criteria were used. The incidence was lower than expected even when the less strict criteria were used. The more accurate incidence of Buerger's disease among the general population can be obtained by performing careful prospective study that is participated in by not only vascular surgeons, but also the other medical specialists with utilizing the strict diagnostic criteria.

Keyword

Buerger's disease; Thromboangiitis obliterans

MeSH Terms

Age of Onset
Arteries
Epidemiologic Studies
Female
Humans
Incidence
Korea*
Lower Extremity
Phlebitis
Risk Factors
Smoke
Smoking
Specialization
Thromboangiitis Obliterans*
Tobacco
Upper Extremity
Veins
Smoke
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