J Korean Sleep Res Soc.  2014 Dec;11(2):45-49. 10.13078/jksrs.14008.

Sleep Disorders in Patients with Parkinson's Disease

• You S
• Cho YW

• KMID: 2202629
• DOI: http://doi.org/10.13078/jksrs.14008

Abstract

Parkinson's disease (PD) is traditionally characterized by a combination of the cardinal motor symptoms of bradykinesia, rigidity, tremor-at-rest, and loss of postural reflex. However, several recent studies have emphasized frequency and serious impact on quality of life by various non-motor symptoms including cognitive abnormalities, mood disorders, autonomic dysfunctions, impaired olfaction, pain, and sleep disorders. Sleep disorders are being increasingly recognized as main non-motor symptom of PD. Sleep disorders, which include the excessive daytime drowsiness, sleep attack, sleep fragmentation, restless legs syndrome, nightmare, and rapid eye movement sleep behavioral disorder are complained by the many of PD patients. Clinical feature, pathophysiology, evaluation tool, and treatment option of sleep disorders are discussed in this review.

Keyword

Parkinson disease; Sleep disorders

MeSH Terms

Dreams
Humans
Hypokinesia
Mood Disorders
Parkinson Disease*
Quality of Life
Reflex
Restless Legs Syndrome
Sleep Deprivation
Sleep Wake Disorders*
Sleep Stages
Sleep, REM
Smell