J Korean Soc Transplant.  2015 Mar;29(1):9-15. 10.4285/jkstn.2015.29.1.9.

Management of Opportunistic Infections after Organ Transplantation

Affiliations
  • 1Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. mkju@yuhs.ac

Abstract

Solid organ transplantation is a therapeutic option for end-stage organ diseases. However, complications including infection and graft rejection, which are related to immunosuppressive therapy, remain the major causes of morbidity and mortality following solid organ transplantation. The optimal approach to infection in solid organ transplant recipients is prevention; failing this, prompt and aggressive diagnosis and therapy are essential. In addition, the epidemiology of infections after solid organ transplantation has shifted as a result of changes in immunosuppressive strategies and improved survival. Immunosuppression must be linked with appropriate vaccinations, donor and recipient screening, patient education regarding infectious risks and lifestyle, monitoring, and antimicrobial prophylaxis.

Keyword

Organ transplantation; Infection; Immunosuppression
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