J Korean Rheum Assoc.  1998 Mar;5(1):103-107.

A case of Limited Scleroderma Associated with Antiphospholipid Syndrome

Abstract

The antiphospholipid syndrome is characterized by arterial thrombosis, venous thrombosis, pregnancy wastage, and thrombocytopenia associated with a persis tently positive lupus anticoagulant and/or moderate to high positive anticardiolipin antibodies(IgG or IgM). The antiphospholipid antibodies have been detected in many medical conditions, but the antiphospholipid syndrome (APS) has mainly been restricted to the primary antiphospholipid syndrome and APS associated with systemic lupus erythematosus. Rarely, the APS has been reported in other autoimmune disorders in the literature. We describe a woman with a limited form of scleroderma and the APS manifested by complete occlusion of left axillary artery with probable thrombotic occlusive nature, thrombocytope nia, prolonged aPTT, and persistently positive lupus anticoagulant.

Keyword

Scleroderma; Antiphospholipid syndrome; Lupus anticoagulant, Scleroderma; Antiphospholipid syndrome; Lupus anticoagulant

MeSH Terms

Antibodies, Antiphospholipid
Antiphospholipid Syndrome*
Axillary Artery
Female
Humans
Lupus Coagulation Inhibitor
Lupus Erythematosus, Systemic
Pregnancy
Scleroderma, Limited*
Thrombocytopenia
Thrombosis
Venous Thrombosis
Antibodies, Antiphospholipid
Lupus Coagulation Inhibitor
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