J Korean Soc Transplant.  2014 Mar;28(1):39-42. 10.4285/jkstn.2014.28.1.39.

Successful Pediatric ABO-Incompatible Kidney Transplantation without Pretransplant Plasmapheresis: Report of a Case

Affiliations
  • 1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. ysms91@yuhs.ac
  • 2Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Immunologic responses of infants and younger children differ from those of adults. Therefore, application of different pretransplant strategies for antibody depletion in younger ABO-incompatible transplant recipients is appropriate. A 12-month-old male infant with end stage renal disease after acute tubular necrosis was scheduled to undergo kidney transplantation from an ABO-incompatible living donor. He did not undergo pretransplant plasmapheresis, as the titer of the anti-ABO antibody was less than 1:4. After kidney transplantation, posttransplant renal function and anti-ABO titers were stable until posttransplant 2 years.

Keyword

Pediatric kidney transplantation; ABO-incompatible kidney transplantation; Plasmapheresis
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