J Korean Soc Transplant.  2005 Jun;19(1):69-73.

Disseminated Cytomegalovirus Infection after Renal Transplantation: A Case Report

Affiliations
  • 1Dongsan Kidney Institute, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. k780121@dsmc.or.kr

Abstract

Cytomegalovirus (CMV) remains an important pathogen in organ transplant recipients, and ganciclovir has been the antiviral agent of choice both for prevention and treatment of CMV disease. Recently ganciclovir-resistant cytomegalovirus has been reported with increasing frequency in organ transplant recipient and is an emerging clinical problem in transplant recipients. Ganciclovir-resistant CMV infection has been associated with clinical progression of CMV disease and high mortality even with foscarnet therapy. We report here a case of disseminated ganciclovir-resistant CMV disease in a 34-year-old renal transplant recipient, who died of multiorgan failure despite treatment with both ganciclovir and foscarnet.

Keyword

Cytomegalovirus; Ganciclovir-resistant; Foscarnet; Renal transplantation

MeSH Terms

Adult
Cytomegalovirus Infections*
Cytomegalovirus*
Foscarnet
Ganciclovir
Humans
Kidney Transplantation*
Mortality
Transplantation
Transplants
Foscarnet
Ganciclovir
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