J Korean Radiol Soc.  2003 Aug;49(2):137-142. 10.3348/jkrs.2003.49.2.137.

Screening Mammogram in Health Center: Medical Audit for Six Years

• Kim JY
• Han BK
• Choe YH
• Kim JH

• KMID: 2199964
• DOI: http://doi.org/10.3348/jkrs.2003.49.2.137

Abstract

PURPOSE: To report the findings of a six-year medial oudit performed at our mammographic screening centre, comparing those findings with the follow-up data stored at our hospital and at the Korea Central Cancer Registry.
MATERIALS AND METHODS
We analyzed the findings of 32,289 mammographic examinations of 25,541 women performed at our screening center between 1994 and 1999. For follow-up and outcome monitoring, the guideline of the American College of Radiology Breast Imaging Reporting and Data System (ACR BI-RADS) was used. All mammograms were categorized by means of BI-RADS, and cases in categories 0, 4, and 5 were followed up through a review of our hospital information system. To determine whether any cases were false negative, we compared breast cancer patients registered in our medical record department and in the Korean Central Cancer Registry during the study period, with women whose mammograms were interpreted as normal or benign at our screening center within a year prior to cancer diagnosis.
RESULTS
The mean age of women enrolled in this study was 48.6 years, ten years less than reported in the West. The recall rate was 6.2%. Among 256 women whose final assessment category was 4 or 5, breast cancer was diagnosed in 51. The cancer detection rate was 2.0/1,000 women; positive predictive value 1 (PPV1: PPV, based on abnormal findings at screening examination) was 2.5% of cases and PPV2 (PPV when biopsy or surgical consultation was recommended) was 20%. The most common mammographic finding was microcalcifications only (45%). The rate of minimal breast cancer, including invasive cancer less than 1 cm in diameter and ductal carcinoma in situ, was 72.5%. Node positivity was 27%. Sensitivity was 85.0% based on the tumor registry of our institution's medical record department, and 78.5% based on the tumor registry of the Korea Central Cancer Registry. Specificity was 99.0%.
CONCLUSION
In our study, the cancer detection rate at screening mammography was 2.0/1,000 women. The rate of minimal breast cancer (72.5%) was very high but measurable sensitivity was 78.5%, somewhat lower than the ACR guideline of 85%. To improve the performance of screening mammography, appropriate interpretation of mammography and constant, follow-up and outcome monitoring are important.

Keyword

Breast neoplasms, diagnosis; Breast neoplasms, radiography; Cancer screening

MeSH Terms

Biopsy
Breast
Breast Neoplasms
Carcinoma, Intraductal, Noninfiltrating
Diagnosis
Early Detection of Cancer
Female
Follow-Up Studies
Hospital Information Systems
Humans
Information Systems
Korea
Mammography
Mass Screening*
Medical Audit*
Medical Records
Sensitivity and Specificity