J Lung Cancer.
2010 Dec;9(2):106-109. 10.6058/jlc.2010.9.2.106.
Tumor Lysis Syndrome Induced by Radiotherapy in Non-Small Cell Lung Cancer
- Affiliations
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- 1Department of Internal Medicine, Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea. kshryj@wonkwang.ac.kr
- 2Department of Pathology, Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.
- 3Department of Radiology, Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.
- KMID: 2199919
- DOI: http://doi.org/10.6058/jlc.2010.9.2.106
Abstract
- Tumor lysis syndrome (TLS) is an oncologic emergency that is characterized by numerous metabolic abnormalities, including hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia and increased serum creatinine. This syndrome is common for tumors with rapid cell turnover and growth rates, and for bulky tumors with high sensitivity to anti-neoplastic treatments. Hence, TLS is a well-recognized clinical problem in hematologic malignancies. TLS is rarely observed to be induced in solid tumors by chemotherapy. Herein we present the second case of TLS that developed during radiotherapy in a patient with non-small cell lung cancer.
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