J Korean Neurol Assoc.  2009 Nov;27(4):424-427.

Myopathy Following Ingestion of Ma-huang (Ephedra)-based Herbal Remedy

Affiliations
  • 1Department of Neurology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea. bumchun.seo@samsung.com

Abstract

Ma-huang (Ephedra sinica) is a herb that exhibits sympathomimetic activity. We report a patient with acquired myopathy following ingestion of a Ma-huang-based herbal remedy for 6 months. A 50-year-old woman was admitted for progressive muscular weakness. An electrodiagnostic study and muscle biopsy sampling revealed generalized active myopathy with nonspecific inflammation. It appears that Ma-huang, along with Raynaud's phenomenon and pericardial effusion, may be a causative agent of myopathy. As such, attention should be paid to the possibility that herbal medication with Ma-huang can result in myopathy.

Keyword

Ephedra; Ma-huang; Muscular diseases

MeSH Terms

Biopsy
Eating
Ephedra
Female
Humans
Inflammation
Middle Aged
Muscle Weakness
Muscles
Muscular Diseases
Pericardial Effusion
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