J Korean Med Assoc.  2011 Sep;54(9):953-956. 10.5124/jkma.2011.54.9.953.

Therapy for idiopathic precocious puberty in children

  • 1Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Korea. 64sks@khnmc.or.kr
  • 2Department of Pharmacy, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Pharmacy, Seoul, Korea.


The incidence of idiopathic precocious puberty is rapidly increasing in Korea. The most common medication used for treatment is a gonadotropin releasing hormone agonist. However, there is some debate regarding the indication and timing of treatment, and the dosage of the medication, because there are many factors that can affect growth in children after delaying puberty. Also, there are new medications that can potentially delay the puberty with children, for example, gonadotropin releasing hormone antagonists and aromatase inhibitors which require extensive further study.


Precocious puberty; Gonadotropin-releasing hormone; Agonist
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