J Korean Acad Oral Health.  2013 Mar;37(1):25-30. 10.11149/jkaoh.2013.37.1.25.

A study on the correlation between urinary fluoride/creatinine ratio, fluoride concentration of drinking water, urine and fingernail in preschool children

  • 1Department of Dental Hygiene, Daewon University College, Gangneung, Korea.
  • 2Department of Preventive and Public Health Dentistry, Research Institute of Oral Science, Gangneung-Wonju National University College of Dentistry, Gangneung, Korea. feeljsh@gwnu.ac.kr


OBJECTIVES: This study aimed to confirm the efficacy of the urinary fluoride concentration/creatinine ratio for monitoring fluorine intake in fluoridated and non-fluoridated communities.
The correlations among the fluoride concentration in drinking water and that in the urine and fingernails of 52 preschool children (age, 60-72 months) from fluoridated and non-fluoridated communities were analyzed.
The urinary fluoride concentration/creatinine ratio had a relatively high correlation with the fluoride concentration in drinking water (Pearson's correlation coefficient, 0.606; P<0.05). Further, this ratio was significantly positively correlated with the urinary fluoride concentration (Pearson's correlation coefficient, 0.374; P<0.01). However, there was no significant correlation between this ratio and the fluoride concentration in fingernails (Pearson's correlation coefficient, 0.145; P>0.05).
The findings of this study suggest that the urinary fluoride concentration/creatinine ratio in children can be utilized as an index for monitoring excess fluoride intake in fluoridated communities.


Fingernail fluoride concentration; Fluoridation; Fluoride monitoring; Urinary fluoride concentration; Urinary fluoride/creatinine ratio
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