J Korean Orthop Assoc.  1999 Feb;34(1):247-253.

Septic Hip in a Child due to H.influenzae: Problems with a Recent Experience

Abstract

We report a case of acute septic arthritis of the hip in a child due to H. influenzae with review of the problems encountered. A one year and 9 months-old male child was admitted because of fever, limping and restlessness of 48-hour duration. Under the impression of septic arthritis of the right hip, blind broad-spectrum antibiotic regimen was initially instituted. Fever subsided immediately and two blood cultures yielded no growth, as did joint tapping. But fever recurred on the 8th day of admission. MRI demonstrated fluid collection in the right hip. Arthrotomy yielded thin pus. The antibiotic regimen was shifted to vancomycin, according to the culture report of S. aureus. However, spiking fever continued. On the 4th week of admission, recheck MRI demonstrated fluid collection in and out of the hip joint. A second arthrotomy yielded frank pus. H. influenzae was reported in pus culture for the first time, being susceptive only to chloramphenicol. Fever was down to normal temperature after injection of urfamycin. Radiograph on the 17th day after the 2nd arthrotomy revealed posterior dislocation of the right hip. MRI demonstrated granulation tissue within the acetabulum. Open reduction confirmed granulation tissue without pus. This case suggests: 1. Routine blind antibiotic regimen for gram-positive and negative organisms in the initial phase of treatment may fail in the rare case of H. influenzae. This may lead the surgeon to miss the optimum time of surgical intervention despite early diagnosis, 2. Arthrotomy may fail if not followed by antibiotics sensitive to the pathogen. 3. Delayed pathologic dislocation may ensue due to invasion of granulation tissue.

Keyword

Hip; Septic arthritis; H,influenzae

MeSH Terms

Acetabulum
Anti-Bacterial Agents
Arthritis, Infectious
Child*
Chloramphenicol
Dislocations
Early Diagnosis
Fever
Granulation Tissue
Hip Joint
Hip*
Humans
Infant
Influenza, Human
Joints
Magnetic Resonance Imaging
Male
Psychomotor Agitation
Suppuration
Thiamphenicol
Vancomycin
Anti-Bacterial Agents
Chloramphenicol
Thiamphenicol
Vancomycin
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