J Korean Neurosurg Soc.  2007 Aug;42(2):149-152.

Primary Cerebellar Hodgkin's Lymphoma

Affiliations
  • 1Department of Neurosurgery, College of Medicine, Brain Tumor Institute Dong-A University, Busan, Korea. kukim@donga.ac.kr
  • 2Department of Pathology, College of Medicine, Brain Tumor Institute Dong-A University, Busan, Korea.
  • 3Department of Diagnostic Radiology, Brain Tumor Institute College of Medicine, Dong-A University, Busan, Korea.
  • 4Department of Onco-radiology, Brain Tumor Institute College of Medicine, Dong-A University, Busan, Korea.

Abstract

Authors report a very rare case of primary Hodgkin's lymphoma limited to the cerebellum. A 64-year-old female patient presented with headache, nausea, and vomiting. Magnetic resonance imaging of the brain revealed a nodular enhancing mass in the left cerebellar hemisphere. Tumor was removed totally with retromastoid suboccipital approach. Diagnosis was Hodgkin's lymphoma of mixed cellularity type, consisting of a dense mixed inflammatory infiltrate containing scattered large atypical mononuclear Hodgkin cells and multinucleated Reed-Sternberg cells. Systemic work-up for the Hodgkin's lymphoma was followed with negative result. Postoperative radiation therapy was given and the patient is disease-free at 16 months after the operation.

Keyword

Cerebellar tumor; Hodgkin's lymphoma; CNS involvement

MeSH Terms

Brain
Cerebellar Neoplasms
Cerebellum
Diagnosis
Female
Headache
Hodgkin Disease*
Humans
Magnetic Resonance Imaging
Middle Aged
Nausea
Reed-Sternberg Cells
Vomiting
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