J Korean Soc Neonatol.  2004 May;11(1):81-86.

Successful Long Term Antifungal Agent Therapy for Renal Candidiasis without Surgical Drainage in a Very Low Birth Weight Infant

• Park JH
• Choi IJ
• Kim SM
• Jung JH
• Kim GH

Abstract

Improved survival rate of premature infants requiring intensive care lead into an increased risk for nosocomial infections such as disseminated fungal infection. Neonatal candida sepsis has become one of the most important causes of neonatal morbidity and mortality. The most common site of end organ involvement in premature infants with candidemia is the kidney. But no consensus has been reached concerning the treatment of candidemia in the newborn. We recently experienced a case of premature infant who was diagnosed as renal candidiasis with microabscess formation due to Candida Albicans and patient was treated successfully with long term liposomal amphotericin B and fluconazole therapy without surgical drainage.

Keyword

Renal candidiasis; Liposomal amphotericin B; Fluconazole; Prematurity

MeSH Terms

Amphotericin B
Candida
Candida albicans
Candidemia
Candidiasis*
Consensus
Cross Infection
Drainage*
Fluconazole
Humans
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight*
Critical Care
Kidney
Mortality
Sepsis
Survival Rate
Amphotericin B
Fluconazole