J Korean Geriatr Soc.  2013 Sep;17(3):138-142. 10.4235/jkgs.2013.17.3.138.

A Case of Vertebral Osteomyelitis With Epidural Abscess Caused by Mycobacterium intracellulare in a Rheumatoid Arthritis Patient

Affiliations
  • 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. paihj@hanyang.ac.kr
  • 2Department of Radiology, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Mycobacterium avium complex (MAC) is the most common pathogen in nontuberculous mycobacterial lung diseases, but vertebral osteomyelitis caused by MAC is rare. We experienced a case of vertebral osteomyelitis with epidural abscess in a rheumatoid arthritis patient who received immunosuppressive agents. Initial assessment was tuberculous vertebral osteomyelitis, and then treated with antituberculous drugs. Fifty-six days later, Mycobacterium intracellulare was identified from abscess culture and drugs were altered to clarithromycin, rifabutin, and ethambutol. After 3 months of M. intracellulare treatment, the radiological findings showed increases of epidural abscess. According to the suseptibility, the patient received intravenous amikacin for four weeks, and then, oral ciprofloxacin in addition to clarithromycin, rifabutin, and ethambutol. The patient is being treated with the medication for 13 months and currently showing slow improvements.

Keyword

Mycobacterium intracellulare; Nontuberculous mycobacteria; Osteomyelitis

MeSH Terms

Abscess
Amikacin
Arthritis, Rheumatoid
Ciprofloxacin
Clarithromycin
Epidural Abscess
Ethambutol
Humans
Immunosuppressive Agents
Lung Diseases
Mycobacterium
Mycobacterium avium Complex
Nontuberculous Mycobacteria
Osteomyelitis
Rifabutin
Amikacin
Ciprofloxacin
Clarithromycin
Ethambutol
Immunosuppressive Agents
Rifabutin
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