J Korean Med Assoc.  2009 May;52(5):472-481. 10.5124/jkma.2009.52.5.472.

Asbestosis Epidemics Caused by Non-occupational Neighborhood Exposure

• Ahn YS
• Kim HR

• KMID: 2188009
• DOI: http://doi.org/10.5124/jkma.2009.52.5.472

Abstract

Asbestos is a naturally occurring mineral in the Earth's crust, and it is not confined to the historic and current asbestos mining areas, but rather quite commonly encountered in certain geological environments across the world. The middle-west side of the Korean Peninsula (Chungnam province) has been composed of numerous talc and asbestos ore deposits derived from serpentine and dolomite. These areas have experienced epidemics of malignant mesothelioma and pleural plaques as a result of non-occupational "neighborhood" exposure and naturally occurring asbestos (NOA) exposure. However, asbestosis epidemics from environmental exposure were rare because asbestosis needs relatively high concentration of asbestos exposure. This review summarizes asbestosis epidemics which occurred in the residents who have lived past or current asbestos mining areas and natural in-place asbestos deposits (or asbestos-like mineral deposits) in the world, including Korean asbestosis endemics that occurred in Chungnam province, which has many historic asbestos mining. Also, this manuscript will describe effective public policies for managing NOA, minimizing potential hazards, and protecting public health from asbestos exposure.

Keyword

Asbestosis; Asbestos mining; Neighborhood exposure; Naturally occurring asbestos (NOA)

MeSH Terms

Asbestos
Asbestosis
Calcium Carbonate
Environmental Exposure
Magnesium
Mesothelioma
Mining
Public Health
Public Policy
Residence Characteristics
Talc
Asbestos
Calcium Carbonate
Magnesium
Talc

Reference

1. De Vuyst P, Karjalainen A, Dumortier P, Pairon JC, Mons E, Brochard P, Teschler H, Tossavainen A, Gibbs A. Guidelines for mineral fibre analyses in biological samples: Report of the ERS Working Group. European Respiratory Society. Eur Respir J. 1998. 11:1416–1426.

2. Yano E, Wang ZM, Wang XR, Wang MZ, Lan YJ. Cancer mortality among workers exposed to amphibole-free chrysotile asbestos. Am J Epidemiol. 2001. 154:538–543.

3. Li L, Sun TD, Zhang X, Lai RN, Li XY, Fan XJ, Morinaga K. Cohort studies on cancer mortality among workers exposed only to chrysotile asbestos: a meta-analysis. Biomed Environ Sci. 2004. 17:459–468.

4. Hein MJ, Stayner LT, Lehman E, Dement JM. Follow-up study of chrysotile textile workers: cohort mortality and exposure-response. Occup Environ Med. 2007. 64:616–625.

5. Comba P, Gianfagna A, Paoletti L. Pleural mesothelioma cases in Biancavilla are related to a new fluoro-edenite fibrous amphibole. Arch Environ Health. 2003. 58:229–232.

6. Baris I, Simonato L, Artvinli M, Pooley F, Saracci R, Skidmore J, Wagner C. Epidemiological and environmental evidence of the health effects of exposure to erionite fibres: a four-year study in the Cappadocian region of Turkey. Int J Cancer. 1987. 39:10–17.

7. Emri S, Demir A, Dogan M, Akay H, Bozkurt B, Carbone M, Baris I. Lung diseases due to environmental exposures to erionite and asbestos in Turkey. Toxicol Lett. 2002. 127:251–257.

8. Baris YI, Grandjean P. Prospective study of mesothelioma mortality in Turkish villages with exposure to fibrous zeolite. J Natl Cancer Inst. 2006. 98:414–417.

9. McDonald JC, McDonald AD, Armstrong B, Sebastien P. Cohort study of mortality of vermiculite miners exposed to tremolite. Br J Ind Med. 1986. 43:436–444.

10. McDonald JC, Harris J, Armstrong B. Mortality in a cohort of vermiculite miners exposed to fibrous amphibole in Libby, Montana. Occup Environ Med. 2004. 61:363–366.

11. Horton DK, Bove F, Kapil V. Select mortality and cancer incidence among residents in various U.S. communities that received asbestos-contaminated vermiculite ore from Libby, Montana. Inhal Toxicol. 2008. 20:767–775.

12. Merchant JA. Human epidemiology: a review of fiber type and characteristics in the development of malignant and nonmalignant disease. Environ Health Perspect. 1990. 88:287–293.

13. Fitzgerald EF, Stark AD, Vianna N, Hwang SA. Exposure to asbestiform minerals and radiographic chest abnormalities in a talc mining region of upstate New York. Arch Environ Health. 1991. 46:151–154.

14. Miller A. Mesothelioma in household members of asbestosexposed workers: 32 United States cases since 1990. Am J Ind Med. 2005. 47:458–462.

15. Magnani C, Ivaldi C, Botta M, Terracini B. Pleural malignant mesothelioma and environmental asbestos exposure in Casale Monferrato, Piedmont. Preliminary analysis of a casecontrol study. Med Lav. 1997. 88:302–309.

16. Pasetto R, Comba P, Marconi A. Mesothelioma associated with environmental exposures. Med Lav. 2005. 96:330–337.

17. Dee P. Armstrong P, Wilson AG, Dee P, Hansell DM, editors. Inhalational lung diseases. Imaging of diseases of the chest. 2000. 3rd ed. London: Mosby;485.

18. Seidman H, Selikoff IJ, Hammond EC. Short-term asbestos work exposure and long-term observation. Ann N Y Acad Sci. 1979. 330:61–89.

19. Brodkin CA, Rosenstock L. Rosenstock L, Cullen MR, Brodkin CA, Redlich CA, editors. Asbestosis and asbestos-related pleural disease. Textbook of clinical occupational and environmental medicine. 2005. 2nd ed. Philadelphia: Elsevier;365.

20. Stayner L, Smith R, Bailer J, Gilbert S, Steenland K, Dement J, Brown D, Lemen R. Exposure-response analysis of risk of respiratory disease associated with occupational exposure to chrysotile asbestos. Occup Environ Med. 1997. 54:646–652.

21. Koskinen K, Rinne JP, Zitting A, Tossavainen A, Kivekäs J, Reijula K, Roto P, Huuskonen MS. Asbestos, asbestosis, and cancer: the Helsinki criteria for diagnosis and attribution. Scand J Work Environ Health. 1997. 23:311–316.

22. Begin R, Samet JM, Shaikh RA. Harber P, Schenker MB, Balmes JR, editors. Asbestos. Occupational and environmental respiratory disease. 1997. St Louis: Mosby;298.

23. Lippmann M. Effects of fiber characteristics on lung deposition, retention, and disease. Environ Health Perspect. 1990. 88:311–317.

24. Karjalainen A, Pukkala E, Kauppinen T, Partanen T. Incidence of cancer among Finnish patients with asbestos-related pulmonary or pleural fibrosis. Cancer Causes Control. 1999. 10:51–57.

25. Oksa P, Klockars M, Karjalainen A, Huuskonen MS, Vattulainen K, Pukkala E, Nordman H. Progression of asbestosis predicts lung cancer. Chest. 1998. 113:1517–1521.

26. Berry G. Mortality of workers certified by pneumoconiosis medical panels as having asbestosis. Br J Ind Med. 1981. 38:130–137.

27. Peters GA, Peters BJ. Neuberger M, editor. Pathology, immunology and gene therapy. Sourcebook on asbestos diseases. 1998. New-York: Lexis Law.

28. Dyken JJ, Wheeler JA. ATSDR's experience with community exposure to "naturally occurring asbestos". J Environ Health. 2008. 70:74–76.

29. Harper M. 10th Anniversary Critical Review: Naturally occurring asbestos. J Environ Monit. 2008. 10:1394–1408.

30. Wagner JC, Sleggs CA, Marchand P. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. Br J Ind Med. 1960. 17:260–271.

31. Yazicioglu S. Pleural calcification associated with exposure to chrysotile asbestos in southeast Turkey. Chest. 1976. 70:43–47.

32. Baris YI, Sahin AA, Ozesmi M, Kerse I, Ozen E, Kolacan B, Altinörs M, Göktepeli A. An outbreak of pleural mesothelioma and chronic fibrosing pleurisy in the village of Karain/Urgüp in Anatolia. Thorax. 1978. 33:181–192.

33. McConnochie K, Simonato L, Mavrides P, Christofides P, Pooley FD, Wagner JC. Mesothelioma in Cyprus: the role of tremolite. Thorax. 1987. 42:342–347.

34. Constantopoulos SH, Theodoracopoulos P, Dascalopoulos G, Saratzis N, Sideris K. Metsovo lung outside Metsovo. Endemic pleural calcifications in the ophiolite belts of Greece. Chest. 1991. 99:1158–1161.

35. Goldberg P, Goldberg M, Marne MJ, Hirsch A, Tredaniel J. Incidence of pleural mesothelioma in New Caledonia: a 10- year survey (1978 -1987). Arch Environ Health. 1991. 46:306–309.

36. Viallat JR, Boutin C, Steinbauer J, Gaudichet A, Dufour G. Pleural effects of environmental asbestos pollution in Corsica. Ann N Y Acad Sci. 1991. 643:438–443.

37. Sichletidis L, Daskalopoulou E, Tsarou V, Pnevmatikos I, Chloros D, Vamvalis C. Five cases of pleural mesothelioma with endemic pleural calcifications in a rural area in Greece. Med Lav. 1992. 83:326–329.

38. Paoletti L, Batisti D, Bruno C, Di Paola M, Gianfagna A, Mastrantonio M, Nesti M, Comba P. Unusually high incidence of malignant pleural mesothelioma in a town of eastern Sicily: an epidemiological and environmental study. Arch Environ Health. 2000. 55:392–398.

39. Zeren EH, Gümürdülü D, Roggli VL, Zorludemir S, Erkisi M, Tuncer I. Environmental malignant mesothelioma in southern Anatolia: a study of fifty cases. Environ Health Perspect. 2000. 108:1047–1050.

40. Magnani C, Dalmasso P, Biggeri A, Ivaldi C, Mirabelli D, Terracini B. Increased risk of malignant mesothelioma of the pleura after residential or domestic exposure to asbestos: a case-control study in Casale Monferrato, Italy. Environ Health Perspect. 2001. 109:915–919.

41. Metintas S, Metintas M, Ucgun I, Oner U. Malignant mesothelioma due to environmental exposure to asbestos: follow-up of a Turkish cohort living in a rural area. Chest. 2002. 122:2224–2229.

42. Luo S, Liu X, Mu S, Tsai SP, Wen CP. Asbestos related diseases from environmental exposure to crocidolite in Dayao, China. I. Review of exposure and epidemiological data. Occup Environ Med. 2003. 60:35–41.

43. Liu XZ, Luo SQ, Wang ZM, Wang MZ, Zhan CL. An investigation of crocidolite contamination and mesothelioma in a rural area of China. Biomed Environ Sci. 1990. 3:156–165.

44. Luo S, Mu S, Zhan C. A retrospective cohort study[1987-1995] of malignant neoplasm in a country contaminated with crocidolite. Chin J Ind Hyg Occup Dis. 1997. 15:272–276.

45. Mu S, Luo S, Yang H. A retrospective cohort study on the mortality of rural area in Da-yao county. Modern Prev Med. 1998. 25:63–65.

46. Baris YI, Bilir N, Artvinli M, Sahin AA, Kalyoncu F, Sebastien P. An epidemiological study in an Anatolian village environmentally exposed to tremolite asbestos. Br J Ind Med. 1988. 45:838–840.

47. Yazicioglu S, Ilçayto R, Balci K, Sayli BS, Yorulmaz B. Pleural calcification, pleural mesotheliomas, and bronchial cancers caused by tremolite dust. Thorax. 1980. 35:564–569.

48. Metintas M, Ozdemir N, Hillerdal G, Uçgun I, Metintas S, Baykul C, Elbek O, Mutlu S, Kolsuz M. Environmental asbestos exposure and malignant pleural mesothelioma. Respir Med. 1999. 93:349–355.

49. Karakoca Y, Emri S, Cangir AK, Baris YI. Environmental pleural plaques asbestos and fibrous zeolite exposure in Turkey. Indoor Built Environ. 1997. 6:100–105.

50. Metintas M, Metintas S, Hillerdal G, Ucgun I, Erginel S, Alatas F, Yildirim H. Nonmalignant pleural lesions due to environmental exposure to asbestos: a field-based, cross-sectional study. Eur Respir J. 2005. 26:875–880.

51. Siemiatycki J, Richardson L, Straif K, Latreille B, Lakhani R, Campbell S, Rousseau MC, Boffetta P. Listing occupational carcinogens. Environ Health Perspect. 2004. 112:1447–1459.

52. Baris B, Demir AU, Shehu V, Karakoca Y, Kisacik G, Baris YI. Environmental fibrous zeolite (erionite) exposure and malignant tumors other than mesothelioma. J Environ Pathol Toxicol Oncol. 1996. 15:183–189.

53. Baris YI, Artvinli M, Sahin AA, Sebastien P, Gaudichet A. Diffuse lung fibrosis due to fibrous zeolite (erionite) exposure. Eur J Respir Dis. 1987. 70:122–125.

54. Peipins LA, Lewin M, Campolucci S, Lybarger JA, Miller A, Middleton D, Weis C, Spence M, Black B, Kapil . Radiographic abnormalities and exposure to asbestos-contaminated vermiculite in the community of Libby, Montana, USA. Environ Health Perspect. 2003. 111:1753–1759.

55. Agency for Toxic Substances and Disease Registry (ATSDR). ATSDR. Mortality in Libby, Montana 1979-1998. Toxicological profile for asbestos. 2002. Atlanta GA: ATSDR.

56. National Institute of Environmental Research (NIER). Health risk assessment due to neighborhood asbestos exposure for residents have lived near asbestos mining and factory area. 2009. Incheon: NIER;in press.

57. Ahn YS, Kim HU, Kim CY, Park JS, Kim JS, Kang DR, Kim HR, Kim HS. The prevalence of asbestos-related pleural thickness and the estimation of asbestos-related mesothelioma in Korea. Research results report (2007-123-1054) of Occupational Safety and Health Agency (OSHRI). 2007. Incheon: OSHRI.

58. Moon YH. Epidemiological survey of asbestosis in asbestos miners and the inhabitants. The Korean Central Journal of Medicine. 1979. 37:169–178.

59. Anderson HA, Lilis R, Daum SM, Selikoff IJ. Asbestosis among household contacts of asbestos factory workers. Ann N Y Acad Sci. 1979. 330:387–399.

60. Aberle DR, Gamsu G, Ray CS, Feuerstein IM. Asbestosrelated pleural and parenchymal fibrosis: detection with highresolution CT. Radiology. 1988. 166:729–734.

61. Aberle DR, Gamsu G, Ray CS. High-resolution CT of benign asbestos-related diseases: clinical and radiographic correlation. Am J Roentgenol. 1988. 151:883–891.