J Korean Neurol Assoc.  1999 Nov;17(6):886-890.

A Case of Alzheimer's Disease Manifesting as Posterior Cortical Atrophy

Affiliations
  • 1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine.
  • 2Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine.
  • 3Department of Neurology, College of Medicine, Inha University.

Abstract

A subgroup of patients with progressive degenerative dementia that begins with higher visual dysfunction has been referred to as posterior cortical atrophy (PCA). A 55-year-old woman presented with progressive visual disturbance for 4 years, which was followed by geographical disorientation, impairment of writing and calculation, and memory distur-bance. Neuropsychological deficits were characterized by Balint syndrome, visuospatial dysfunction, prosopagnosia, Gerstmann syndrome and apraxia. Brain MRI showed mild diffuse atrophy. F18-FDG-PET disclosed bilateral occipi-totemporoparietal hypometabolism, more pronounced on the right. Biopsy from right temporal lobe revealed neu-ropathological findings consistent with Alzheimer's disease.

Keyword

Posterior cortical atrophy; Alzheimer's disease; Dementia, Balint syndrome
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