J Korean Orthop Assoc.  2012 Oct;47(5):321-329. 10.4055/jkoa.2012.47.5.321.

Platelet-Rich Plasma Therapy for Knee Joint Problems - Review of the Literature, Current Practice and Legal Perspectives in Korea - : Secondary Pulblication

• Park YG
• Han SB
• Song SJ
• Kim TJ
• Ha CW

• KMID: 2185315
• DOI: http://doi.org/10.4055/jkoa.2012.47.5.321

Abstract

Platelet-rich plasma (PRP) is a concentrate extract of platelets from autologous blood, and represents a possible treatment option for the stimulation and acceleration of soft-tissue healing and regeneration in orthopedics. Currently, the availability of devices for outpatient preparation and delivery contributes to the increase in the clinical use of PRP therapy in practical setting of orthopedic fields. However, there is still paucity of scientific evidence in the literature to prove efficacy of PRP therapy for the treatment of ligament or tendon problems around the knee joint. Moreover, strong evidence from well-designed clinical trials to support the PRP therapy for osteoarthritis of the knee joint is yet scanty in the literature. Scientific studies need to be performed to assess clinical indications, efficacy, and safety of PRP, and this will require high powered randomized controlled trials. Nonetheless, some hospitals exaggeratedly advertise PRP procedures, as the ultimate treatment and a novel technology with abundant scientific evidence for the treatment of knee problems. As a matter of fact, PRP protocols are currently approved only for the use in clinical trials and research, and are not allowed for treatment purpose by any institutions in Korea. At present, clinical use of PRP therapy for ligament or tendon problems or osteoarthritis of knee joint is defined as an illegal medical practice, regardless of whether it is performed as a sole procedure or as a part of prolotherapy, because the safety and validity are not yet approved by the Ministry of Health and Welfare, and Health Insurance Review and Assessment Service. Practicing physicians should remember that injection of PRP to patients by imposing medical charge is still illegal, as per the current medical laws in Korea.

Keyword

platelet-rich plasma; osteoarthritis; ligaments; tendons; knee joint

MeSH Terms

Acceleration
Blood Platelets
Fees and Charges
Humans
Insurance, Health
Joints
Jurisprudence
Knee
Knee Joint
Korea
Ligaments
Orthopedics
Osteoarthritis
Osteoarthritis, Knee
Outpatients
Platelet-Rich Plasma
Regeneration
Tendons

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