J Korean Neurol Assoc.  2010 Aug;28(3):209-213.

Encephalitis Lethargica With Catatonia

Affiliations
  • 1Department of Neurology, Seoul National University College of Medicine, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seoul, Korea. neuroksy@snu.ac.kr
  • 2Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea.
  • 3Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea.

Abstract

Encephalitis lethargica (EL) is an acute or subacute central nervous system (CNS) infectious disorder presenting with pharyngitis followed by sleep disorder, basal ganglia signs (particularly parkinsonism), and neuropsychiatric sequelae. We report a 67-year-old man who had hypersomnolence, oculogyric crisis, akinetic mutism, parkinsonism, and malignant catatonia, which represented the stereotypic movement disorder with additional features of hyperthermia. His symptoms dramatically improved after steroid pulse therapy, indicating that EL syndrome could be a postinfectious neurological autoimmune CNS disorder.

Keyword

Encephalitis; Catatonia; Parkinsonism

MeSH Terms

Aged
Akinetic Mutism
Basal Ganglia
Catatonia
Central Nervous System
Disorders of Excessive Somnolence
Encephalitis
Fever
Humans
Parkinsonian Disorders
Pharyngitis
Stereotypic Movement Disorder
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