J Korean Med Assoc.  2007 Sep;50(9):785-795. 10.5124/jkma.2007.50.9.785.

Treatment of Cervical Cancer

Affiliations
  • 1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Korea. ksboo308@plaza.snu.ac.kr

Abstract

The treatment modality of cervical cancer depends on the stage and tumor size. In nonadvanced, non-bulky cervical cancers, both surgery and chemoradiation are equally effective. Therefore, the treatment modality is chosen based on the complication rate and the quality of life after treatment. When risk factors such as the positive resection margin, lymph node metastasis, parametrial invasion, bulky disease over 4cm, deep stromal invasion, and lymphovascular space involvement are present after surgery, adjuvant chemoradiation should be performed. In non-advanced, bulky cervical cancers, the optimal treatment is controversial. As a primary therapy, chemoradiation, neoadjuvant chemotherapy and radical surgery, or radical surgery is used. In advanced cervical cancers, chemoradiation is the treatment of choice. However, the indication of paraaortic radiation is still controversial.

Keyword

Cervical cancer; Radical hysterectomy; Chemoradiation

MeSH Terms

Drug Therapy
Lymph Nodes
Neoplasm Metastasis
Quality of Life
Risk Factors
Uterine Cervical Neoplasms*

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