J Korean Med Assoc.  2006 Jan;49(1):63-69. 10.5124/jkma.2006.49.1.63.

Treatment of Acne

  • 1Department of Dermatology, Soonchunhyang University College of Medicine and Hospital, Korea. snolomas@hosp.sch.ac.kr


Acne vulgaris is a self-limited disease, seen primarily in adolescents. Most cases of acne are pleomorphic, presenting various lesions consisting of comedones, pustules, and nodules. Although it has been traditionally classified as a disease of the sebaceous gland, it actually involves the pilosebaceous unit. There are four major principles in the treatment of acne: (1) correct the altered pattern of follicular keratinization; (2) decrease the sebaceous gland activity; (3) decrease the follicular bacterial population; and (4) produce anti-inflammatory effect. The natural course of acne varies greatly, and therefore, the determination of the therapeutic efficacy of medications for the treatment of acne is far from being simple.


Acne; Pilosebaceous Unit; Comedone; Retinoid

MeSH Terms

Acne Vulgaris*
Sebaceous Glands


  • Figure 1 Pathophysiology of ance


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