J Korean Med Assoc.  2004 Sep;47(9):889-894. 10.5124/jkma.2004.47.9.889.

Medical Treatment of Osteoporosis

• Byun DW

• KMID: 2183506
• DOI: http://doi.org/10.5124/jkma.2004.47.9.889

Abstract

Osteoporosis is a common and significant health problem in more than 1/3 of postmenopausal women. Strategies for the medical treatment of osteoporosis are primarily based on decreasing the resorption component of bone turnover by estrogen, alendronate, risedronate, raloxifene, or calcitonine. Recently there are therapies that are focused on increasing bone formation by fluoride, parathyroid hormone, or strontium ranelate. This article reviews the medical treatment of osteoporosis focusing on the pharmacokinetic effects on the bone metabolism, anti-fracture effects, usage of the drugs and their side effects.

Keyword

Osteoporosis; Treatment; Side effect

MeSH Terms

Alendronate
Calcitonin
Estrogens
Female
Fluorides
Humans
Metabolism
Osteogenesis
Osteoporosis*
Parathyroid Hormone
Raloxifene Hydrochloride
Risedronate Sodium
Strontium
Alendronate
Calcitonin
Estrogens
Fluorides
Parathyroid Hormone
Strontium