1. Abraham C, Cho JH. Inflammatory bowel disease. N Engl J Med. 2009; 361:2066–2078. PMID:
19923578.
Article
2. Anderson CA, Boucher G, Lees CW, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011; 43:246–252. PMID:
21297633.
3. Franke A, McGovern DP, Barrett JC, et al. Genome-wide metaanalysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010; 42:1118–1125. PMID:
21102463.
4. Yang SK, Hong M, Zhao W, et al. Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. Gut. 2014; 63:80–87. PMID:
23850713.
Article
5. Yang SK, Hong M, Zhao W, et al. Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians. Inflamm Bowel Dis. 2013; 19:954–966. PMID:
23511034.
Article
6. Jostins L, Ripke S, Weersma RK, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012; 491:119–124. PMID:
23128233.
7. Yamazaki K, McGovern D, Ragoussis J, et al. Single nucleotide polymorphisms in
TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet. 2005; 14:3499–3506. PMID:
16221758.
Article
8. Kakuta Y, Kinouchi Y, Negoro K, Takahashi S, Shimosegawa T. Association study of
TNFSF15 polymorphisms in Japanese patients with inflammatory bowel disease. Gut. 2006; 55:1527–1528. PMID:
16966713.
Article
9. Yang SK, Lim J, Chang HS, et al. Association of
TNFSF15 with Crohn's disease in Koreans. Am J Gastroenterol. 2008; 103:1437–1442. PMID:
18422820.
10. Yue TL, Ni J, Romanic AM, et al. TL1, a novel tumor necrosis factor-like cytokine, induces apoptosis in endothelial cells. Involvement of activation of stress protein kinases (stress-activated protein kinase and p38 mitogen-activated protein kinase) and caspase-3-like protease. J Biol Chem. 1999; 274:1479–1486. PMID:
9880523.
Article
11. Migone TS, Zhang J, Luo X, et al. TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity. 2002; 16:479–492. PMID:
11911831.
Article
12. Izumi Y, Hirai S, Tamai Y, Fujise-Matsuoka A, Nishimura Y, Ohno S. A protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvation. J Biol Chem. 1997; 272:7381–7389. PMID:
9054438.
Article
13. Xu XL, Wu LC, Du F, et al. Inactivation of human
SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. Cancer Res. 2001; 61:7943–7949. PMID:
11691816.
14. Lee JH, Byun DS, Lee MG, et al. Frequent epigenetic inactivation of
hSRBC in gastric cancer and its implication in attenuated p53 response to stresses. Int J Cancer. 2008; 122:1573–1584. PMID:
18059034.
Article
15. Zöchbauer-Müller S, Fong KM, Geradts J, et al. Expression of the candidate tumor suppressor gene
hSRBC is frequently lost in primary lung cancers with and without DNA methylation. Oncogene. 2005; 24:6249–6255. PMID:
15940253.
Article
16. Lee JH, Kang MJ, Han HY, et al. Epigenetic alteration of
PRKCDBP in colorectal cancers and its implication in tumor cell resistance to TNFa-induced apoptosis. Clin Cancer Res. 2011; 17:7551–7562. PMID:
21980136.
Article
17. Kim JW, Kim HJ, Lee CK, et al. Elevation of PRKCDBP, a novel transcriptional target of TNF-α, and its downregulation by infliximab in patients with ulcerative colitis. Dig Dis Sci. 2014; 59:2947–2957. PMID:
25052149.
Article
18. Tong SY, Lee JM, Ki KD, Seol HJ, Choi YJ, Lee SK. Genetic polymorphism of PRKCDBP is associated with an increased risk of endometrial cancer. Cancer Invest. 2012; 30:642–645. PMID:
23020606.
Article
19. Gasche C, Scholmerich J, Brynskov J, et al. A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis. 2000; 6:8–15. PMID:
10701144.
Article
20. Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature. 2003; 425:577–584. PMID:
14534577.
Article
21. Gaur U, Aggarwal BB. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol. 2003; 66:1403–1408. PMID:
14555214.
Article
22. Lee SH. Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases. Intest Res. 2015; 13:11–18. PMID:
25691839.
Article
23. Ferguson LR, Huebner C, Petermann I, et al. Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk. World J Gastroenterol. 2008; 14:4652–4661. PMID:
18698679.
Article
24. Thiebaut R, Kotti S, Jung C, et al.
TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort. Am J Gastroenterol. 2009; 104:384–391. PMID:
19174806.
Article
25. Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 2001; 411:599–603. PMID:
11385576.
Article
26. MM FernandoCR StevensEC Walsh. Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet. DOI:
10.1371/journal.pgen.1000024. Published online 25 April 2008.
Article
27. McGovern DP, Jones MR, Taylor KD, et al. Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. Hum Mol Genet. 2010; 19:3468–3476. PMID:
20570966.
Article
28. Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008; 40:955–962. PMID:
18587394.
29. Brant SR. Promises, delivery, and challenges of inflammatory bowel disease risk gene discovery. Clin Gastroenterol Hepatol. 2013; 11:22–26. PMID:
23131344.
Article
30. Cho JH, Brant SR. Recent insights into the genetics of inflammatory bowel disease. Gastroenterology. 2011; 140:1704–1712. PMID:
21530736.
Article