J Gynecol Oncol.  2008 Dec;19(4):261-264. 10.3802/jgo.2008.19.4.261.

Leiomyosarcoma of the vagina: a case report and review from the literature

Affiliations
  • 1Department of Obstetrics and Gynecology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea. dcpark@catholic.ac.kr

Abstract

Leiomyosarcomas comprise fewer than 2% of all malignant vaginal neoplasms. Due to their rarity, treatment for vaginal leiomyosarcomas have not been determined. We describe a 66 year old woman with vaginal leiomyosarcoma, which presented as a large palpable mass with vaginal spotting. Complete surgical excision was accomplished and after surgery, she underwent radiation therapy. Tumor recurrence was not detected for the last 5 years and now her general condition is very good. This is a rare case of leiomyosarcoma arising in vagina and we report the results of successful treatment.

Keyword

Leiomyosarcoma; Vagina

MeSH Terms

Female
Humans
Leiomyosarcoma
Metrorrhagia
Recurrence
Vagina
Vaginal Neoplasms

Figure

  • Fig. 1 Pre-operative MR images. They show that the about 6×5.7×5.2 cm sized heterogenous signal mass in posterolateral portion of the vagina. (A) T1-weighted axial MR image, (B) T2-weighted axial MR image, (C) T2-weighted sagittal MR image, (D) T2-weighted coronal MR image.

  • Fig. 2 (A) There are marked increased spindle cells (H & E, ×40), (B) In focal area, we could see some foci of degeneration (H & E, ×100). (C, D) Spindle cells revealed moderate nuclear atypism with frequent mitosis (H & E, ×400).


Reference

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2. Ahram J, Lemus R, Schiavello HJ. Leiomyosarcoma of the vagina: case report and literature review. Int J Gynecol Cancer. 2006. 16:884–891.
3. Tavassoli FA, Norris HJ. Smooth muscle tumors of the vagina. Obstet Gynecol. 1979. 53:689–693.
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5. Creasman WT, Phillips JL, Menck HR. The National Cancer Data Base report on cancer of the vagina. Cancer. 1998. 83:1033–1040.
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