Ann Dermatol.  2010 Feb;22(1):57-60. 10.5021/ad.2010.22.1.57.

An Unusual Clinical Presentation of Kimura's Disease Occurring on the Buttock of a Five-year-old Boy

• Choi WJ
• Hur J
• Ko JY
• Yeo KY
• Kim JS
• Yu HJ

• KMID: 2172039
• DOI: http://doi.org/10.5021/ad.2010.22.1.57

Abstract

Kimura's disease is a rare inflammatory disorder of unknown etiology primarily seen in young Asian males. It is characterized by painless subcutaneous masses, blood and tissue eosinophilia, and markedly elevated serum immunoglobulin E (IgE) levels. Clinically, the subcutaneous nodules occur predominantly in the head and neck. However, we report the case of a five-year-old boy presenting with an asymptomatic solitary brown pigmented nodule on the left buttock diagnosed with Kimura's disease. Here we describe the diagnosis and treatment of this unusual case.

Keyword

Buttock; Kimura's disease; Preschool child

MeSH Terms

Asian Continental Ancestry Group
Buttocks
Child, Preschool
Eosinophilia
Head
Humans
Immunoglobulin E
Immunoglobulins
Male
Neck
Immunoglobulin E
Immunoglobulins

Figure

• 

  Fig. 1 Clinical presentation of the current case. (A) Solitary brown pigmented nodule on the left buttock. (B) Closer view.

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  Fig. 2 Histopathological findings were consistent with the Kimura's disease. (A) Numerous lymphoid follicles with germinal centers and stromal sclerosis (H&E, ×100). (B) Lymphoid follicle with germinal center surrounded by eosinophils and proliferating vessels (H&E, ×200). (C) Eosinophilic microabscess was observed in the deep dermis (H&E, ×200). (D) Massive infiltration of eosinophils. Vascular endothelial cells were flattened (not epithelioid or histiocytoid) (H&E, ×400).

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