Ann Dermatol.  2011 Feb;23(1):76-80. 10.5021/ad.2011.23.1.76.

A Case of Primary Cutaneous CD4 Positive Small/medium T Cell Lymphoma

• Choi M
• Park SY
• Park HS
• Byun HJ
• Cho KH

• KMID: 2171958
• DOI: http://doi.org/10.5021/ad.2011.23.1.76

Abstract

Primary cutaneous CD4 positive small/medium T cell lymphoma (PCSM-TCL) is a provisional entity in the new WHO-EORTC classification for cutaneous lymphoma, and it is a rare disease with a favorable clinical course. PCSM-TCL may present with different clinical and pathologic features associated with the biologic behavior of the disease. Herein we report on a 63-year-old woman with multiple, multifocal, erythematous to violaceous papules and plaques that progressed despite local radiotherapy.

Keyword

CD4; Cutaneous T cell lymphoma; Small/medium

MeSH Terms

Female
Humans
Lymphoma
Lymphoma, T-Cell
Lymphoma, T-Cell, Cutaneous
Middle Aged
Rare Diseases

Figure

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  Fig. 1 Multiple erythematous to violaceous papules and plaque on the face (A), abdomen (B) and thigh (C).

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  Fig. 2 (A) The skin biopsy obtained from the right thigh reveals a dense lymphoid infiltrate in the dermis (H&E, ×40). (B) The infiltrate is mainly small/medium sized pleomorphic lymphocytes (H&E, ×200).

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  Fig. 3 Most of the lymphocytes express CD3 (A) and CD4 (B). A few CD8 positive cells (C) and reactive CD20 cells (D) are also present (×100).

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