Ann Dermatol.  2011 Aug;23(3):386-388. 10.5021/ad.2011.23.3.386.

Childhood Granulomatous Periorificial Dermatitis

• Kim YJ
• Shin JW
• Lee JS
• Park YL
• Whang KU
• Lee SY

• KMID: 2171936
• DOI: http://doi.org/10.5021/ad.2011.23.3.386

Abstract

Childhood granulomatous periorificial dermatitis (CGPD), also known as facial Afro-Caribbean childhood eruption (FACE), is a distinctive granulomatous form of perioral dermatitis. It is a condition of unknown etiology, characterized by monomorphous, small, papular eruptions around the mouth, nose and eyes that histopathologically show a granulomatous pattern. It affects prepubescent children of both sexes and typically persists for several months but resolved without scarring. We report a 9 year-old girl with multiple, discrete, monomorphic, papular eruptions of 2-months duration on the perioral and periocular areas. Histopathological examination demonstrated upper dermal and perifollicular granulomatous infiltrate.

Keyword

Childhood granulomatous periorificial dermatitis

MeSH Terms

Child
Cicatrix
Dermatitis
Dermatitis, Perioral
Eye
Humans
Mouth
Nose

Figure

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  Fig. 1 (A) A close up view of the papular lesions around the mouth. Numerous firm papules seen on the erythematous base in a perioral distribution. (B) A close-up view of the papular lesions around the eyes. Several yellow-brown dome-shaped papules can seen in the lower eyelid.

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  Fig. 2 Skin biopsy from the perioral area shows upper and perifollicular granuloma with adjacent lymphocytes. A granuloma is comprised of epithelioid cells and lymphocytes (H&E, ×200).

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