Ann Dermatol.  2013 May;25(2):259-260. 10.5021/ad.2013.25.2.259.

Long-Term Follow-Up of Refractory Mycosis Fungoides Which Achieved Remission with the Addision of Isotretinoin to Methotrexate and Psoralen Plus Ultraviolat A Therapy

Affiliations
  • 1Department of Dermatology, Eulji University Hospital, Daejeon, Korea. dwkoo@eulji.ac.kr

Abstract

No abstract available.


MeSH Terms

Ficusin
Follow-Up Studies
Isotretinoin
Methotrexate
Mycosis Fungoides
Ficusin
Isotretinoin
Methotrexate

Figure

  • Fig. 1 (A) Edematous dusky red to erythematous patches on the back and the left leg before treatment. (B) Remission on the back and left leg with addition of isotretinoin to methotrexate and psoralen plus ultraviolet A therapy.

  • Fig. 2 (A) Epidermotrophism with clustered atypical lymphocytes in the epidermis and dense lymphocytic infiltrate with hyperchromatic nuclei in the dermis (H&E, ×40; inset: H&E, ×200). (B) The result of T-cell receptor-gamma gene rearrangement showed the monoclonality in polymerase chain reaction-heteroduplex analysis. Marker (lane M), specimen (lane S), negative control (lane N), positive control (lane P).


Reference

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2. Shin HS, Huh CH, Cho KH. Treatment of the early mycosis fungoides. Korean J Dermatol. 2007. 45:983–988.
3. O'Brien S, Vose JM, Kantarjian HM. Management of hematologic malignancies. 2010. 1st ed. New York: Cambridge University Press;440.
4. Trautinger F. Phototherapy of mycosis fungoides. Photodermatol Photoimmunol Photomed. 2011. 27:68–74.
Article
5. Thomsen K, Molin L, Volden G, Lange Wantzin G, Hellbe L. 13-cis-retinoic acid effective in mycosis fungoides. A report from the Scandinavian Mycosis Fungoides Group. Acta Derm Venereol. 1984. 64:563–566.
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