Ann Dermatol.  2015 Aug;27(4):389-393. 10.5021/ad.2015.27.4.389.

Patch Testing with Dental Screening Series in Oral Disease

• Kim TW
• Kim WI
• Mun JH
• Song M
• Kim HS
• Kim BS
• Kim MB
• Ko HC

• KMID: 2171494
• DOI: http://doi.org/10.5021/ad.2015.27.4.389

Abstract

BACKGROUND
The oral mucosa is constantly exposed to several irritants and allergens including dental materials, but the role of contact allergy in oral disease is obscure.
OBJECTIVE
To analyze positive patch test results in patients with oral diseases and evaluate the clinical relevance of oral diseases with contact allergy to dental materials.
METHODS
We retrospectively analyzed patch test results with dental screening series in 44 patients with oral disease from 2004~2011.
RESULTS
Oral diseases included oral lichen planus (54.5%), cheilitis (27.3%), burning mouth syndrome (9.1%), and others (9.1%). Thirty-one of 44 patients (70.5%) had positive reactions to one or more allergens. The most commonly detected allergens were gold sodium thiosulfate (25.0%) and nickel sulfate (25.0%), followed by potassium dichromate (22.7%), cobalt (15.9%), palladium (6.8%), mercury (4.5%), copper (4.5%), and methylhydroquinone (4.5%). Six of 24 patients with oral lichen planus had a symptom in areas adjacent to dental materials and positive patch test reactions to allergens contained in the suspected dental materials.
CONCLUSION
Patch tests with dental screening series are worth considering for oral diseases, especially for oral lichen planus.

Keyword

Dental materials; Dental screening series; Oral disease; Patch tests

MeSH Terms

Allergens
Burning Mouth Syndrome
Cheilitis
Cobalt
Copper
Dental Materials
Gold Sodium Thiosulfate
Humans
Hypersensitivity
Irritants
Lichen Planus, Oral
Mass Screening*
Mouth Mucosa
Nickel
Palladium
Patch Tests*
Potassium Dichromate
Retrospective Studies
Allergens
Cobalt
Copper
Dental Materials
Gold Sodium Thiosulfate
Irritants
Nickel
Palladium
Potassium Dichromate

Figure

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  Fig. 1 Patch test results with dental screening series in patients with oral disease.

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