Clin Psychopharmacol Neurosci.  2015 Apr;13(1):1-11. 10.9758/cpn.2015.13.1.1.

Tobacco Use in Bipolar Disorder

  • 1Department of Applied Sciences, RMIT, Bundoora, Australia.
  • 2IMPACT Strategic Research Centre, School of Medicine, Deakin University, Barwon Health, Geelong, Australia.
  • 3Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.
  • 4Department of Psychiatry, University of Melbourne, Parkville, Australia.
  • 5Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.
  • 6Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia.
  • 7Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, CIBERSAM, IiSGM, School of Medicine, Universidad Complutense, Madrid, Spain.
  • 8Research Unit, Mental Health Services, Region of Southern Denmark, Esbjerg, Denmark.
  • 9Centre for Mental Health and Wellbeing Research, School of Psychology, Deakin University, Burwood, Australia.


Tobacco use in mental health in general and bipolar disorder in particular remains disproportionally common, despite declining smoking rates in the community. Furthermore, interactions between tobacco use and mental health have been shown, indicating the outcomes for those with mental health disorders are impacted by tobacco use. Factors need to be explored and addressed to improve outcomes for those with these disorders and target specific interventions for people with psychiatric illness to cease tobacco smoking. In the context of bipolar disorder, this review explores; the effects of tobacco smoking on symptoms, quality of life, suicidal behaviour, the biological interactions between tobacco use and bipolar disorder, the interactions between tobacco smoking and psychiatric medications, rates and factors surrounding tobacco smoking cessation in bipolar disorder and suggests potential directions for research and clinical translation. The importance of this review is to bring together the current understanding of tobacco use in bipolar disorder to highlight the need for specific intervention.


Bipolar disorder; Smoking; Smoking cessation; Quality of life; Psychotropic drugs
Full Text Links
  • CPN
  • Twitter
  • Facebook
Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: